Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays vital
roles in modulating metabolism, immunity, and oncogenesis. ATF3 acts as a hub of the …

Colorectal cancer (CRC) is one of the most common malignancies with high prevalence and
low 5-year survival. CRC is a heterogeneous disease with a complex, genetic and …

The serine synthesis pathway (SSP) involving metabolic enzymes phosphoglycerate
dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine …

We propose a new multi-network-based strategy to integrate different layers of genomic
information and use them in a coordinate way to identify driving cancer genes. The multi …

Background Dysregulation of the common stress responsive transcription factor ATF3 has
been causally linked to many important human diseases such as cancer, atherosclerosis …

Bladder cancer is associated with high recurrence and mortality rates due to metastasis. The
elucidation of metastasis suppressors may offer therapeutic opportunities if their …

Simple Summary Although the overexpression of CDCA8 is frequently observed in
hepatocellular carcinoma (HCC) tissues, the functions of CDCA8 during HCC development …

Objective: This study aimed to investigate the expression and significance of ATF-3 in
laryngeal squamous cell carcinoma (LSCC). Methods: Expression of ATF-3 was examined …

The placenta, a pivotal organ in mammalian reproduction, allows nutrient exchange and
hormonal signaling between the mother and the developing fetus. Understanding its …

Atherosclerosis, the pathophysiological basis of most malignant cardiovascular diseases,
remains a global concern. Transcription factors play a key role in regulating cell function and …