[HTML][HTML] Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications

F Leblond, SC Davis, PA Valdés, BW Pogue - Journal of photochemistry …, 2010 - Elsevier
Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

Upconverting nanoparticles for pre‐clinical diffuse optical imaging, microscopy and sensing: Current trends and future challenges

CT Xu, Q Zhan, H Liu, G Somesfalean… - Laser & Photonics …, 2013 - Wiley Online Library
Upconverting nanoparticles (UCNPs) are a class of recently developed luminescent
biomarkers that–in several aspects–are superior to organic dyes and quantum dots. UCNPs …

Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications

NC Deliolanis, R Kasmieh, T Wurdinger… - … of biomedical optics, 2008 - spiedigitallibrary.org
The discovery of new fluorescent proteins (FPs) that emit in the far-red part of the spectrum,
where light absorption from tissue is significantly lower than in the visible, offers the …

Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media

CT Xu, N Svensson, J Axelsson, P Svenmarker… - Applied Physics …, 2008 - pubs.aip.org
Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of
exogenous molecular markers in tissue, degrading the quality of the collected data. In this …

Deep tissue optical and optoacoustic molecular imaging technologies for pre-clinical research and drug discovery

D Razansky, NC Deliolanis, C Vinegoni… - Current …, 2012 - ingentaconnect.com
For centuries, biological discoveries were based on optical imaging, in particular microscopy
but also several chromophoric assays and photographic approaches. With the recent …

Visualization of pulmonary inflammation using noninvasive fluorescence molecular imaging

J Haller, D Hyde, N Deliolanis… - Journal of Applied …, 2008 - journals.physiology.org
The ability to visualize molecular processes and cellular regulators of complex pulmonary
diseases such as asthma, chronic obstructive pulmonary disease (COPD), or adult …

Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles

C Vinegoni, D Razansky, SA Hilderbrand, F Shao… - Optics letters, 2009 - opg.optica.org
We report on a systematic study of upconverting fluorescence signal generation within turbid
phantoms and real tissues. An accurate three-point Green's function, describing the forward …

The importance of being red

BW Rice, CH Contag - Nature biotechnology, 2009 - nature.com
The importance of being red | Nature Biotechnology Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Fundamentals of optical imaging

RB Schulz, W Semmler - Molecular Imaging I, 2008 - Springer
Optical imaging techniques offer simplistic while highly sensitive modalities for molecular
imaging research. In this chapter, the major instrumental necessities for microscopic and …

In vivo study of photosensitizer pharmacokinetics by fluorescence transillumination imaging

M Shirmanova, E Zagaynova… - … of biomedical optics, 2010 - spiedigitallibrary.org
The possibility of in vivo investigation of the pharmacokinetics of photosensitizers by means
of fluorescence transillumination imaging is demonstrated. An animal is scanned in the …