Production of monoclonal antibodies (mAbs) is a well-known method used to synthesize a
large number of identical antibodies, which are molecules of huge importance in medicine …

Even if the performances of bioprocesses can be significantly improved by model-based
control, there often remains a tradeoff between model complexity and control robustness …

This work proposes a dynamic modeling procedure applied to biomethane production from
microalgae residual co-digestion. A two-stage anaerobic digestion representation is …

In this paper, the application of a robust nonlinear model predictive control (NMPC)
framework to mammalian cell cultures is proposed, dealing with possible large kinetic …

Multi-enzymatic reactions are effective alternatives to complex chemical syntheses, using
milder reaction conditions, and generating less waste. One essential engineering problem …

Following the recent advent of Process Analytical Technologies, dataset production has
undergone significant leverage. In this new abundance of data, isolating meaningful …

Multi-enzymatic reactions can successfully replace complex chemical syntheses, using
milder reaction conditions, and generating less waste. The present model-based analysis …

For process optimisation purposes, it is of interest to monitor the concentration of
monoclonal antibody produced by cultures of hybridoma cells. However, the on-line …

Following the recent advent of Process Analytical Technologies, dataset production has
undergone significant leverage. In this new abundance of data, isolating meaningful …

In this study, a dynamic model of a Vero cell culture‐based dengue vaccine production
process is developed. The approach consists in describing the process dynamics as …