Our immune system is based on the close collaboration of the innate and adaptive immune
systems for the rapid detection of any threats to the host. Recognition of pathogen-derived …

Abstract Interleukin 33 (IL-33) is a member of the IL-1 family of cytokines with a growing
number of target cells and a plethora of biological functions. Although it has commonalities …

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel
Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen and dried …

Targeted inhibition of cytokine pathways provides opportunities to understand fundamental
biology in vivo in humans. The IL-33 pathway has been implicated in the pathogenesis of …

Helper T (Th) cell subsets direct immune responses by producing signature cytokines. Th2
cells produce IL-4, IL-5, and IL-13, which are important in humoral immunity and protection …

Allergic rhinitis affects the quality of life of millions of people worldwide. Air pollution not only
causes morbidity, but nearly 3 million people per year die from unhealthy indoor air …

Eosinophils can regulate local immune and inflammatory responses, and their accumulation
in the blood and tissue is associated with several inflammatory and infectious diseases …

Abstract Interleukin-33 (IL-33), a newly described member of the IL-1 family, is expressed by
many cell types following pro-inflammatory stimulation and is thought to be released on cell …

Innate immunity provides the first line of response to invading pathogens and a variety of
environmental insults. Recent studies identified novel subsets of innate lymphoid cells that …

Asthma is a very complex and heterogeneous disease that is characterized by airway
inflammation and airway hyper-reactivity (AHR). The pathogenesis of asthma is associated …