[HTML][HTML] Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
AB Lorusso, JA Carrara, CDN Barroso, FF Tuon… - International journal of …, 2022 - mdpi.com
Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …
parallel with new antibiotics, leading to a major global public health crisis over time …
[HTML][HTML] Bacterial multidrug efflux pumps at the frontline of antimicrobial resistance: an overview
L Huang, C Wu, H Gao, C Xu, M Dai, L Huang, H Hao… - Antibiotics, 2022 - mdpi.com
Multidrug efflux pumps function at the frontline to protect bacteria against antimicrobials by
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
[HTML][HTML] Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy
J Ma, X Song, M Li, Z Yu, W Cheng, Z Yu… - Microbiological …, 2023 - Elsevier
Bacterial drug resistance has become a global public health threat, among which the
infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable …
infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable …
Challenges and opportunities in biological funneling of heterogeneous and toxic substrates beyond lignin
Significant developments in the understanding and manipulation of microbial metabolism
have enabled the use of engineered biological systems toward a more sustainable energy …
have enabled the use of engineered biological systems toward a more sustainable energy …
[HTML][HTML] “Superbugs” with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China
D Pu, J Zhao, K Chang, X Zhuo, B Cao - Science Bulletin, 2023 - Elsevier
Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …
[HTML][HTML] Pharmaceutical approaches on antimicrobial resistance: prospects and challenges
The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has
become a significant public health problem globally. The management of this issue using …
become a significant public health problem globally. The management of this issue using …
[HTML][HTML] Biocidal resistance in clinically relevant microbial species: a major public health risk
Antimicrobial resistance is one of the greatest dangers to public health of the 21st century,
threatening the treatment and prevention of infectious diseases globally. Disinfection, the …
threatening the treatment and prevention of infectious diseases globally. Disinfection, the …
Expression of RND efflux pumps mediated antibiotic resistance in Pseudomonas aeruginosa clinical strains
Abstract Resistance-Nodulation-Division (RND) efflux pumps are responsible for multidrug
resistance in Pseudomonas aeruginosa. The present study aimed to evaluate the …
resistance in Pseudomonas aeruginosa. The present study aimed to evaluate the …
Tackling multidrug-resistant Staphylococcus aureus by natural products and their analogues acting as NorA efflux pump inhibitors
G Kumar, AK Tudu - Bioorganic & Medicinal Chemistry, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is a pathogen responsible for various community and
hospital-acquired infections with life-threatening complications like bacteraemia …
hospital-acquired infections with life-threatening complications like bacteraemia …
[HTML][HTML] Host-bacterial pathogen communication: the wily role of the multidrug efflux pumps of the MFS family
M Pasqua, MC Bonaccorsi di Patti, G Fanelli… - Frontiers in Molecular …, 2021 - frontiersin.org
Bacterial pathogens are able to survive within diverse habitats. The dynamic adaptation to
the surroundings depends on their ability to sense environmental variations and to respond …
the surroundings depends on their ability to sense environmental variations and to respond …