Four decades ago, Iran encountered rapid sociodemographic and economic transitions.
This review was carried out to investigate the trend of cardiovascular disease (CVD) …

Background Dexmedetomidine (DEX) is a highly selective alpha2 adrenoceptor agonist with
broad pharmacological effects, including sedation, analgesia, anxiolysis, and sympathetic …

Inflammatory activation is increasingly recognized as a nonconventional risk factor for
arrhythmias, and experimental studies provided robust evidence that this association is …

Atrial fibrillation (AF), the most common progressive and age-related cardiac arrhythmia,
affects millions of people worldwide. AF is associated with common risk factors, including …

Pre-existing Ca2+ handling abnormalities constitute the arrhythmogenic substrate in
patients developing postoperative atrial fibrillation (POAF), a common complication after …

The adipose tissue has long been thought to represent a passive source of triglycerides and
fatty acids. However, extensive data have demonstrated that the adipose tissue is also a …

Atrial fibrillation (AF) is the most common sustained arrhythmia. Individuals with AF have a 5-
fold increased risk of stroke, 3-fold increased risk of heart failure, and almost 2-fold …

Background and aims This study aimed to investigate the role of C-reactive protein (CRP) in
atrial fibrillation (AF) from epidemiological and genetic perspectives. Methods and results …

Clinical observation and ex vivo studies have established a strong association between
inflammation and postoperative atrial fibrillation (POAF). However, it is unclear whether the …

Background: The pathophysiology of postoperative atrial fibrillation (POAF) is multifactorial.
Inflammation and increased oxidative stress play a significant role in POAF development …