Food safety considerations and research priorities for the cultured meat and seafood industry

KJ Ong, J Johnston, I Datar, V Sewalt… - … Reviews in Food …, 2021 - Wiley Online Library
Cell‐cultured meat and seafood offer a sustainable opportunity to meet the world's
increasing demand for protein in a climate‐changed world. A responsible, data‐driven …

Reactivation of telomerase in cancer

SC Akincilar, B Unal, V Tergaonkar - Cellular and Molecular Life Sciences, 2016 - Springer
Activation of telomerase is a critical step in the development of about 85% of human
cancers. Levels of Tert, which encodes the reverse transcriptase subunit of telomerase, are …

Early events in the pathogenesis of epithelial ovarian cancer

CN Landen Jr, MJ Birrer, AK Sood - Journal of Clinical Oncology, 2008 - ascopubs.org
Ovarian carcinogenesis, as in most cancers, involves multiple genetic alterations. A great
deal has been learned about proteins and pathways important in the early stages of …

Long noncoding RNA BC032469, a novel competing endogenous RNA, upregulates hTERT expression by sponging miR-1207-5p and promotes proliferation in …

MH Lü, B Tang, S Zeng, CJ Hu, R Xie, YY Wu… - Oncogene, 2016 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as new players in gene regulation and are
associated with the development of cancers. To investigate the important role and …

Mutations of p53 and KRAS activate NF-κB to promote chemoresistance and tumorigenesis via dysregulation of cell cycle and suppression of apoptosis in lung cancer …

L Yang, Y Zhou, Y Li, J Zhou, Y Wu, Y Cui, G Yang… - Cancer letters, 2015 - Elsevier
Although mutations of p53 and KRAS and activation of NF-κB signaling have been highly
associated with chemoresistance and tumorigenesis of lung cancer, the interactive …

CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis

G Yang, DG Rosen, G Liu, F Yang, X Guo, X Xiao… - Clinical Cancer …, 2010 - AACR
Purpose: Chemokine receptor CXCR2 is associated with malignancy in several cancer
models; however, the mechanisms involved in CXCR2-mediated tumor growth remain …

[HTML][HTML] Ovarian cancer: pathology, biology, and disease models

DG Rosen, G Yang, G Liu, I Mercado-Uribe… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
Epithelial ovarian cancer, which comprises several histologic types and grades, is the most
lethal cancer among women in the United States. In this review, we summarize recent …

Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer

IG Schauer, AK Sood, S Mok, J Liu - Neoplasia, 2011 - Elsevier
The progression of ovarian cancer, from cell transformation through invasion of normal
tissue, relies on communication between tumor cells and their adjacent stromal …

Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2

G Yang, B Chang, F Yang, X Guo, KQ Cai, X Xiao… - Clinical cancer …, 2010 - AACR
Abstract Purpose: Aurora kinase A (Aurora-A) is known to regulate genomic instability and
tumorigenesis in multiple human cancers. The underlying mechanism, however, is not fully …

A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration

Y Wang, S Chen, Z Yan, M Pei - Cell & Bioscience, 2019 - Springer
Cellular senescence is a major hurdle for primary cell-based tissue engineering and
regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes …