The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

J Zhang, G Chen, P Zhang, J Zhang, X Li, D Gan… - PloS one, 2020 - journals.plos.org
Objective Hepatocellular carcinoma (HCC) has become a pressing health problem facing
the world today due to its high morbidity, high mortality, and late discovery. As a diagnostic …

[PDF][PDF] Current and emerging tools for hepatocellular carcinoma surveillance

N Adeniji, R Dhanasekaran - Hepatology communications, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related mortality worldwide.
Early detection of HCC enables patients to avail curative therapies that can improve patient …

Performance of PIVKA-II for early hepatocellular carcinoma diagnosis and prediction of microvascular invasion

N Poté, F Cauchy, M Albuquerque, H Voitot… - Journal of …, 2015 - Elsevier
Background & Aims Prothrombin induced by vitamin K absence-II (PIVKA-II) is a diagnostic
and surveillance marker for HCC mainly used in Asia, and has also been shown to be a …

[PDF][PDF] A multi‐analyte cell‐free DNA–based blood test for early detection of hepatocellular carcinoma

N Lin, Y Lin, J Xu, D Liu, D Li, H Meng… - Hepatology …, 2022 - Wiley Online Library
The limited performance of guideline‐recommended abdominal ultrasound and serum
alpha‐fetoprotein (AFP) highlights the urgent, unmet need for new biomarkers for more …

Role of the GALAD and BALAD-2 serologic models in diagnosis of hepatocellular carcinoma and prediction of survival in patients

S Berhane, H Toyoda, T Tada, T Kumada… - Clinical …, 2016 - Elsevier
Background & Aims GALAD and BALAD-2 are statistical models for estimating the likelihood
of the presence of hepatocellular carcinoma (HCC) in individual patients with chronic liver …

The GALAD scoring algorithm based on AFP, AFP-L3, and DCP significantly improves detection of BCLC early stage hepatocellular carcinoma

J Best, H Bilgi, D Heider, C Schotten… - Zeitschrift für …, 2016 - thieme-connect.com
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of death in
cirrhotic patients worldwide. The detection rate for early stage HCC remains low despite …

GALAD score detects early-stage hepatocellular carcinoma in a european cohort of chronic hepatitis B and C patients

C Schotten, B Ostertag, JP Sowa, P Manka… - Pharmaceuticals, 2021 - mdpi.com
Despite vaccination programs and direct antiviral treatments, the incidence of virus-related
hepatocellular carcinoma (HCC) remains high, while ultrasound-based detection rates for …

[HTML][HTML] Diagnostic and therapeutic management of hepatocellular carcinoma

F Bellissimo, MR Pinzone, B Cacopardo… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is an increasing health problem, representing the second
cause of cancer-related mortality worldwide. The major risk factor for HCC is cirrhosis. In …

The combination of PIVKA‐II and AFP improves the detection accuracy for HCC in HBV caucasian cirrhotics on long‐term oral therapy

A Loglio, M Iavarone, F Facchetti, D Di Paolo… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Protein induced by vitamin K absence or antagonist‐II (PIVKA‐
II) has been suggested as a serum biomarker for hepatocellular carcinoma (HCC) in Asian …

[HTML][HTML] Current biomarkers for hepatocellular carcinoma: Surveillance, diagnosis and prediction of prognosis

K Schütte, C Schulz, A Link… - World journal of …, 2015 - ncbi.nlm.nih.gov
Biomarkers for surveillance, diagnosis and prediction of prognosis in patients with
hepatocellular carcinoma (HCC) are currently not ready for introduction into clinical practice …