The protective role of dietary polyphenols in urolithiasis: insights into antioxidant effects and mechanisms of action

SY Hong, BL Qin - Nutrients, 2023 - mdpi.com
Urolithiasis is a common urological disease with increasing prevalence and high recurrence
rates around the world. Numerous studies have indicated reactive oxygen species (ROS) …

Oxidative stress and endoplasmic stress in calcium oxalate stone disease: the chicken or the egg?

A Albert, E Paul, S Rajakumar, L Saso - Free radical research, 2020 - Taylor & Francis
Crystal modulators play a significant role in the formation of calcium oxalate stone disease.
When renal cells are subjected to oxalate stress, the loss in cell integrity leads to exposure …

[HTML][HTML] Polydatin protects against calcium oxalate crystal-induced renal injury through the cytoplasmic/mitochondrial reactive oxygen species-NLRP3 inflammasome …

J Liu, J Huang, B Gong, S Cheng, Y Liu, Y Chen… - Biomedicine & …, 2023 - Elsevier
Background Oxidative stress and inflammatory responses are critical factors in calcium
oxalate (CaOx) crystal-induced renal injury. Reactive oxygen species (ROS) are usually …

Resveratrol attenuates oxalate-induced renal oxidative injury and calcium oxalate crystal deposition by regulating TFEB-induced autophagy pathway

Y Wu, Y Xun, J Zhang, H Hu, B Qin, T Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
The oxidative injury of renal tubular epithelial cells caused by inflammation and oxidative
stress induced by hyperoxaluria is an important factor in the kidney calcium oxalate (CaOx) …

Protective effect of pentoxifylline on oxidative renal cell injury associated with renal crystal formation in a hyperoxaluric rat model

H Ozturk, A Cetinkaya, TS Firat, BK Tekce, SE Duzcu… - Urolithiasis, 2019 - Springer
The aim of the study is to investigate the effects of pentoxifylline (PTX) on the renal tubular
cell injury and stone formation in a hyperoxaluric rat model induced by ethylene glycol and …

Aldosterone is involved in the pathogenesis of obesity-related glomerulopathy through activation of Wnt/β-catenin signaling in podocytes

JJ Zhu, YP Chen, M Yang, BL Liu… - Molecular …, 2018 - spandidos-publications.com
Obesity-related glomerulopathy (ORG) is morphologically characterized by
glomerulomegaly with or without observable focal segmental glomerulosclerosis under light …

[HTML][HTML] Resveratrol inhibits calcium oxalate crystal growth, reduces adhesion to renal cells and induces crystal internalization into the cells, but promotes crystal …

P Peerapen, P Putpeerawit, W Boonmark… - Current Research in …, 2024 - Elsevier
Resveratrol is a natural phenolic compound that belongs to stilbenoid group found in
diverse plants. Health benefits and therapeutic potentials of resveratrol have been widely …

Litholytic activities of natural bioactive compounds and their mechanism insights

N El Menyiy, A Khouchlaa, N El Omari, G Zengin… - Applied Sciences, 2021 - mdpi.com
Urolithiasis is a disease characterized by the formation of stones, which are crystalline
accretions that form in the urinary tract from minerals dissolved in the urine. Moreover, it is …

膳食酚类物质抗炎活性与干预炎症信号通路机制研究进展.

赵钜阳, 姚恒喆, 李玉奇, 李越… - Modern Food Science & …, 2024 - search.ebscohost.com
水果, 蔬菜, 谷物, 香料和草药中富含膳食多酚, 这些多酚物质对植物的营养价值和生物活性具有
重要影响. 多酚可与多糖, 蛋白质, 磷脂等大分子物质产生相互作用并影响二者的活性及生物可 …

Early evidence of global dna methylation and hydroxymethylation changes in rat kidneys consequent to hyperoxaluria-induced renal calcium oxalate stones

Y Mehra, P Viswanathan - Cytology and Genetics, 2022 - Springer
Calcium supersaturation in urine during hyperoxaluria can lead to renal calcium oxalate
(CaOx) stone deposition; a condition termed as nephrolithiasis. Recent genetic studies …