BACKGROUND: After breast-conserving surgery, radiotherapy reduces recurrence and
breast cancer death, but it may do so more for some groups of women than for others. We …

Radiation therapy is an integral part of the multidisciplinary management of breast cancer.
Regional lymph node irradiation in younger trials seems to provide superior target coverage …

The therapeutic options for patients with noninvasive or invasive breast cancer are complex
and varied. These NCCN Clinical Practice Guidelines for Breast Cancer include …

Ductal carcinoma in situ (DCIS) of the breast represents a heterogeneous group of
neoplastic lesions in the breast ducts. The goal for management of DCIS is to prevent the …

These NCCN Guidelines Insights highlight the important updates/changes to the surgical
axillary staging, radiation therapy, and systemic therapy recommendations for hormone …

Purpose Controversy exists regarding the optimal margin width in breast-conserving surgery
for invasive breast cancer. Methods A multidisciplinary consensus panel used a meta …

Background Since the introduction of breast-conserving treatment, various radiation doses
after lumpectomy have been used. In a phase 3 randomised controlled trial, we investigated …

Background The optimal fractionation schedule for whole-breast irradiation after breast-
conserving surgery is unknown. Methods We conducted a study to determine whether a …

Breast cancer is the most common malignancy in women in the United States and is second
only to lung cancer as a cause of cancer death. The overall management of breast cancer …

Background Whole breast irradiation (WBI) after conservative surgery for ductal carcinoma
in situ (DCIS) reduces local recurrence. We investigated whether a tumour bed boost after …