Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
In vitro and ex vivo strategies for intracellular delivery
Intracellular delivery of materials has become a critical component of genome-editing
approaches, ex vivo cell-based therapies, and a diversity of fundamental research …
approaches, ex vivo cell-based therapies, and a diversity of fundamental research …
[HTML][HTML] A review of emerging physical transfection methods for CRISPR/Cas9-mediated gene editing
AK Fajrial, QQ He, NI Wirusanti, JE Slansky, X Ding - Theranostics, 2020 - ncbi.nlm.nih.gov
Gene editing is a versatile technique in biomedicine that promotes fundamental research as
well as clinical therapy. The development of Clustered Regularly Interspaced Short …
well as clinical therapy. The development of Clustered Regularly Interspaced Short …
State-of-the-art MEMS and microsystem tools for brain research
JP Seymour, F Wu, KD Wise, E Yoon - Microsystems & …, 2017 - nature.com
Mapping brain activity has received growing worldwide interest because it is expected to
improve disease treatment and allow for the development of important neuromorphic …
improve disease treatment and allow for the development of important neuromorphic …
An enzyme‐coated metal–organic framework shell for synthetically adaptive cell survival
A bioactive synthetic porous shell was engineered to enable cells to survive in an
oligotrophic environment. Eukaryotic cells (yeast) were firstly coated with a β‐galactosidase …
oligotrophic environment. Eukaryotic cells (yeast) were firstly coated with a β‐galactosidase …
Advanced tools and methods for single-cell surgery
A Shakoor, W Gao, L Zhao, Z Jiang… - Microsystems & …, 2022 - nature.com
Highly precise micromanipulation tools that can manipulate and interrogate cell organelles
and components must be developed to support the rapid development of new cell-based …
and components must be developed to support the rapid development of new cell-based …
Intracellular manipulation and measurement with multipole magnetic tweezers
The capability to directly interrogate intracellular structures inside a single cell for
measurement and manipulation is important for understanding subcellular and suborganelle …
measurement and manipulation is important for understanding subcellular and suborganelle …
Mechanical properties of single cells: Measurement methods and applications
Y Hao, S Cheng, Y Tanaka, Y Hosokawa… - Biotechnology …, 2020 - Elsevier
Cell mechanical properties, eg elastic and shear modulus, play vital roles in cell activities
and functions, such as cell growth, cell division, cell motion, and cell adhesion …
and functions, such as cell growth, cell division, cell motion, and cell adhesion …
Robotic micromanipulation: Fundamentals and applications
Robotic micromanipulation is a relatively young field. However, after three decades of
development and evolution, the fundamental physics; techniques for sensing, actuation, and …
development and evolution, the fundamental physics; techniques for sensing, actuation, and …
Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: at a glance
MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …
placed a strong emphasis on cutting-edge nanostructured materials technologies to …