Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

Diaryl ether (DE) is a functional scaffold existing widely both in natural products (NPs) and
synthetic organic compounds. Statistically, DE is the second most popular and enduring …

The drug resistance problem is most acute in the case of bacteria. There is always a need to
develop novel antibacterial drugs with better mechanisms of action. Most of the quinoline …

Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …

Novel sixty three quinoline-3-carbonitrile derivatives were synthesized starting from 6-
substituted-2-hydrazinyl quinoline-3-carbonitrile. The synthesized compounds were …

Quinoline derivatives are considered broad-spectrum pharmacological compounds that
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …

In this study β-lactam derivatives which include 1, 3, 4-thiadiazole and 1, 3, 4-oxadiazole
structure (8a, b) have been achieved by cyclocondensation reaction. The synthesized …

Abstract A series of new 1, 2, 4-triazole and 1, 3, 4-oxadiazole derivatives was obtained via
several steps sequential reactions of phenyl piperazine. Then, these compounds were …

This article briefs about the efforts taken to synthesis, characterize and develop (E)-5-methyl-
2-phenyl-3-(thiophen-2-yl)-7-(thiophen-2-ylmethylene)-3, 3a, 4, 5, 6, 7-hexahydro-2H …