Abstract Exportin 1 (XPO1), also known as chromosome region maintenance protein 1,
plays a crucial role in maintaining cellular homeostasis via the regulated export of a range of …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …

Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

The NCCN Guidelines for Head and Neck (H&N) Cancers provide treatment
recommendations for cancers of the lip, oral cavity, pharynx, larynx, ethmoid and maxillary …

Background Patients with recurrent or metastatic squamous-cell carcinoma of the head and
neck (HNSCC) progressing after first-line platinum regimens have a poor prognosis and few …

This review highlights the evidence-based data to support current best management
practices for patients with recurrent and/or metastatic (R/M) head and neck squamous cell …

Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …

Head and neck cancers account for less than 5% of all cancers and for less than 3% of all
cancer deaths in the United States. The populations at risk for head and neck cancers are …

This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Head and Neck Cancers focuses on glottic laryngeal cancer, which is the most common …

While a large proportion of patients presenting with stage I and II squamous cell carcinoma
of the head and neck (SCCHN) will remain disease free after single modality treatment, the …