Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

RNAs: regulators of bacterial virulence

J Gripenland, S Netterling, E Loh, T Tiensuu… - Nature Reviews …, 2010 - nature.com
RNA-based pathways that regulate protein expression are much more widespread than
previously thought. Regulatory RNAs, including 5′ and 3′ untranslated regions next to the …

High-throughput, kingdom-wide prediction and annotation of bacterial non-coding RNAs

J Livny, H Teonadi, M Livny, MK Waldor - PloS one, 2008 - journals.plos.org
Background Diverse bacterial genomes encode numerous small non-coding RNAs (sRNAs)
that regulate myriad biological processes. While bioinformatic algorithms have proven …

A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles

T Song, F Mika, B Lindmark, Z Liu, S Schild… - Molecular …, 2008 - Wiley Online Library
We discovered a new small non‐coding RNA (sRNA) gene, vrrA of Vibrio cholerae O1 strain
A1552. A vrrA mutant overproduces OmpA porin, and we demonstrate that the 140 nt VrrA …

Identification of small RNAs in Mycobacterium tuberculosis

KB Arnvig, DB Young - Molecular microbiology, 2009 - Wiley Online Library
In spite of being one of our most prominent bacterial pathogens, the presence of small
regulatory RNAs (sRNAs) has not previously been investigated in Mycobacterium …

Prevalence of small base-pairing RNAs derived from diverse genomic loci

PP Adams, G Storz - Biochimica Et Biophysica Acta (BBA)-Gene …, 2020 - Elsevier
Small RNAs (sRNAs) that act by base-pairing have been shown to play important roles in
fine-tuning the levels and translation of their target transcripts across a variety of model and …

Identification of small RNAs in diverse bacterial species

J Livny, MK Waldor - Current opinion in microbiology, 2007 - Elsevier
Small, non-coding bacterial RNAs (sRNAs) have been shown to regulate a plethora of
biological processes. Up until recently, most sRNAs had been identified and characterized …

Identification of 17 Pseudomonas aeruginosa sRNAs and prediction of sRNA-encoding genes in 10 diverse pathogens using the bioinformatic tool …

J Livny, A Brencic, S Lory, MK Waldor - Nucleic acids research, 2006 - academic.oup.com
Abstract sRNAs are small, non-coding RNA species that control numerous cellular
processes. Although it iswidely accepted that sRNAs are encoded by most if not all bacteria …

Experimental discovery of sRNAs in Vibrio cholerae by direct cloning, 5S/tRNA depletion and parallel sequencing

JM Liu, J Livny, MS Lawrence, MD Kimball… - Nucleic acids …, 2009 - academic.oup.com
Direct cloning and parallel sequencing, an extremely powerful method for microRNA
(miRNA) discovery, has not yet been applied to bacterial transcriptomes. Here we present …

High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model–based analyses of transposon-insertion sequencing data

MC Chao, JR Pritchard, YJ Zhang… - Nucleic acids …, 2013 - academic.oup.com
The coupling of high-density transposon mutagenesis to high-throughput DNA sequencing
(transposon-insertion sequencing) enables simultaneous and genome-wide assessment of …