Host and HBV interactions and their potential impact on clinical outcomes
Hepatitis B virus (HBV) is a challenge for global health services, affecting millions and
leading thousands to end-stage liver disease each year. This comprehensive review …
leading thousands to end-stage liver disease each year. This comprehensive review …
Bile acids, gut microbiota, and therapeutic insights in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a prevalent and aggressive liver malignancy. The
interplay between bile acids (BAs) and the gut microbiota has emerged as a critical factor in …
interplay between bile acids (BAs) and the gut microbiota has emerged as a critical factor in …
EASL Clinical Practice Guidelines on hepatitis delta virus
Hepatitis D virus (HDV) is a defective virus that requires the hepatitis B virus to complete its
life cycle and cause liver damage in humans. HDV is responsible for rare acute and chronic …
life cycle and cause liver damage in humans. HDV is responsible for rare acute and chronic …
Structural basis of hepatitis B virus receptor binding
J Asami, JH Park, Y Nomura, C Kobayashi… - Nature Structural & …, 2024 - nature.com
Hepatitis B virus (HBV), a leading cause of developing hepatocellular carcinoma affecting
more than 290 million people worldwide, is an enveloped DNA virus specifically infecting …
more than 290 million people worldwide, is an enveloped DNA virus specifically infecting …
Magnetic‐activated nanosystem with liver‐specific CRISPR nonviral vector to achieve spatiotemporal liver genome editing as hepatitis B therapeutics
Chronic hepatitis B infection remains incurable due to the stable presence of various forms
of hepatitis B virus (HBV) genome, especially the HBV covalently closed circular DNA …
of hepatitis B virus (HBV) genome, especially the HBV covalently closed circular DNA …
[HTML][HTML] May the proton motive force be with you: a plant transporter review
CG Andersen, L Bavnhøj, BP Pedersen - Current Opinion in Structural …, 2023 - Elsevier
As our ecosystems experience challenges associated with climate change, an improved
understanding of the fundamental biochemical processes governing plant physiology is …
understanding of the fundamental biochemical processes governing plant physiology is …
Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP
H Liu, D Zakrzewicz, K Nosol, RN Irobalieva… - Nature …, 2024 - nature.com
Cellular entry of the hepatitis B and D viruses (HBV/HDV) requires binding of the viral
surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting …
surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting …
HBV vaccines: advances and development
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …
Bile acid increase during bulevirtide treatment of hepatitis D is not associated with a decline in HDV RNA
K Deterding, C Xu, K Port, C Dietz‐Fricke… - Journal of viral …, 2023 - Wiley Online Library
Bulevirtide (BLV) is an entry inhibitor blocking entry of HBsAg into hepatocytes by interfering
with the bile acid transporter Na+‐taurocholate co‐transporting polypeptide. We here …
with the bile acid transporter Na+‐taurocholate co‐transporting polypeptide. We here …
Structural basis for hepatitis B virus restriction by a viral receptor homologue
K Shionoya, JH Park, T Ekimoto, JS Takeuchi… - Nature …, 2024 - nature.com
Macaque restricts hepatitis B virus (HBV) infection because its receptor homologue, NTCP
(mNTCP), cannot bind preS1 on viral surface. To reveal how mNTCP loses the viral receptor …
(mNTCP), cannot bind preS1 on viral surface. To reveal how mNTCP loses the viral receptor …