Functional neuroanatomy of the basal ganglia

JL Lanciego, N Luquin… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The “basal ganglia” refers to a group of subcortical nuclei responsible primarily for motor
control, as well as other roles such as motor learning, executive functions and behaviors …

Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease

JA Obeso, MC Rodríguez‐Oroz… - … : official journal of the …, 2008 - Wiley Online Library
The basal ganglia (BG) are a highly organized network, where different parts are activated
for specific functions and circumstances. The BG are involved in movement control, as well …

Pathophysiology of parkinsonism

A Galvan, T Wichmann - Clinical neurophysiology, 2008 - Elsevier
The motor signs of Parkinson's disease are thought to result in large part from a reduction of
the level of dopamine in the basal ganglia. Over the last few years, many of the functional …

Basal ganglia beta oscillations accompany cue utilization

DK Leventhal, GJ Gage, R Schmidt, JR Pettibone… - Neuron, 2012 - cell.com
Beta oscillations in cortical-basal ganglia (BG) circuits have been implicated in normal
movement suppression and motor impairment in Parkinson's disease. To dissect the …

The basal ganglia in Parkinson's disease: current concepts and unexplained observations

JA Obeso, C Marin, C Rodriguez‐Oroz… - Annals of Neurology …, 2008 - Wiley Online Library
The pathophysiology of Parkinson's disease is reviewed in light of recent advances in the
understanding of the functional organization of the basal ganglia (BG). Current emphasis is …

The thalamostriatal system in normal and diseased states

Y Smith, A Galvan, TJ Ellender, N Doig… - Frontiers in systems …, 2014 - frontiersin.org
Because of our limited knowledge of the functional role of the thalamostriatal system, this
massive network is often ignored in models of the pathophysiology of brain disorders of …

The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward.

MD Humphries, TJ Prescott - Progress in neurobiology, 2010 - Elsevier
The basal ganglia are often conceptualised as three parallel domains that include all the
constituent nuclei. The 'ventral domain'appears to be critical for learning flexible behaviours …

Oscillations in the basal ganglia under normal conditions and in movement disorders

P Gatev, O Darbin, T Wichmann - Movement disorders, 2006 - Wiley Online Library
A substantial body of work within the last decade has demonstrated that there is a variety of
oscillatory phenomena that occur in the basal ganglia and in associated regions of the …

Cortical and thalamic innervation of direct and indirect pathway medium-sized spiny neurons in mouse striatum

NM Doig, J Moss, JP Bolam - Journal of Neuroscience, 2010 - Soc Neuroscience
The striatum receives major excitatory inputs from the cortex and thalamus that
predominantly target the spines of medium-sized spiny neurons (MSNs). We aimed to …

Neurocomputational models of basal ganglia function in learning, memory and choice

MX Cohen, MJ Frank - Behavioural brain research, 2009 - Elsevier
The basal ganglia (BG) are critical for the coordination of several motor, cognitive, and
emotional functions and become dysfunctional in several pathological states ranging from …