The emerging role of ATP as a cosolute for biomolecular processes

A Hautke, S Ebbinghaus - Biological Chemistry, 2023 - degruyter.com
ATP is an important small molecule that appears at outstandingly high concentration within
the cellular medium. Apart from its use as a source of energy and a metabolite, there is …

[HTML][HTML] Multiple modes of DNA compaction by protamine

V Ahlawat, HX Zhou - bioRxiv, 2023 - ncbi.nlm.nih.gov
In sperm cells, protamine replaces histones to compact DNA 10–20 times more than in
somatic cells. To characterize the extreme compaction, we employed confocal microscopy …

Electrostatics of salt-dependent re-entrant phase behaviors highlights diverse roles of ATP in biomolecular condensates

YH Lin, TH Kim, S Das, T Pal, J Wessen, LE Kay… - Biophysical …, 2023 - cell.com
Liquid-liquid phase separation (LLPS) involving intrinsically disordered protein regions
(IDRs) is a major physical basis for biomolecular condensates such as intracellular …