Aquaporin 4 and neuromyelitis optica
MC Papadopoulos, AS Verkman - The Lancet Neurology, 2012 - thelancet.com
Neuromyelitis optica is an inflammatory demyelinating disorder of the CNS. The discovery of
circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) …
circulating IgG1 antibodies against the astrocyte water channel protein aquaporin 4 (AQP4) …
Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …
gut microbiota is a key player in communication between these two distant organs. Yet, the …
Treatment of neuromyelitis optica: state-of-the-art and emerging therapies
MC Papadopoulos, JL Bennett… - Nature Reviews …, 2014 - nature.com
Neuromyelitis optica (NMO) is an autoimmune disease of the CNS that is characterized by
inflammatory demyelinating lesions in the spinal cord and optic nerve, potentially leading to …
inflammatory demyelinating lesions in the spinal cord and optic nerve, potentially leading to …
Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
CE Johanson, JA Duncan, PM Klinge, T Brinker… - Cerebrospinal fluid …, 2008 - Springer
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics:
formation rate, pressure, flow, volume, turnover rate, composition, recycling and …
formation rate, pressure, flow, volume, turnover rate, composition, recycling and …
The blood–cerebrospinal fluid barrier: structure and functional significance
CE Johanson, EG Stopa, PN McMillan - The Blood-Brain and Other …, 2011 - Springer
The choroid plexus (CP) of the blood–CSF barrier (BCSFB) displays fundamentally different
properties than blood-brain barrier (BBB). With brisk blood flow (10× brain) and highly …
properties than blood-brain barrier (BBB). With brisk blood flow (10× brain) and highly …
Brain cell volume regulation in hyponatremia: role of sex, age, vasopressin, and hypoxia
JC Ayus, SG Achinger, A Arieff - American Journal of …, 2008 - journals.physiology.org
Hyponatremia is the most common electrolyte abnormality in hospitalized patients. When
symptomatic (hyponatremic encephalopathy), the overall morbidity is 34%. Individuals most …
symptomatic (hyponatremic encephalopathy), the overall morbidity is 34%. Individuals most …
Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury
Repairing trauma to the central nervous system by replacement of glial support cells is an
increasingly attractive therapeutic strategy. We have focused on the less-studied …
increasingly attractive therapeutic strategy. We have focused on the less-studied …
Pregnancy outcomes in aquaporin-4–positive neuromyelitis optica spectrum disorder
Objective: To investigate the association between neuromyelitis optica spectrum disorder
(NMOSD) and pregnancy outcome. Methods: An international cohort of women with …
(NMOSD) and pregnancy outcome. Methods: An international cohort of women with …
Neuromyelitis optica IgG causes placental inflammation and fetal death
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the CNS and
affects women of childbearing age. Most patients with NMO have circulating Abs, termed …
affects women of childbearing age. Most patients with NMO have circulating Abs, termed …
Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution?
Traumatic brain injury (TBI) is one of the leading causes of death and disability in children
and adolescents. The neuropathological sequelae that result from TBI are a complex …
and adolescents. The neuropathological sequelae that result from TBI are a complex …