[HTML][HTML] GAS6/TAM axis as therapeutic target in liver diseases
TAM (TYRO3, AXL, and MERTK) protein tyrosine kinase membrane receptors and their
vitamin K-dependent ligands GAS6 and protein S (PROS) are well-known players in tumor …
vitamin K-dependent ligands GAS6 and protein S (PROS) are well-known players in tumor …
Hepatic immune regulation and sex disparities
P Burra, A Zanetto, B Schnabl, T Reiberger… - Nature Reviews …, 2024 - nature.com
Chronic liver disease is a major cause of morbidity and mortality worldwide. Epidemiology,
clinical phenotype and response to therapies for gastrointestinal and liver diseases are …
clinical phenotype and response to therapies for gastrointestinal and liver diseases are …
Implications of innate immune sexual dimorphism for MASLD pathogenesis and treatment
R Booijink, P Ramachandran, R Bansal - Trends in Pharmacological …, 2024 - cell.com
Growing evidence suggests that metabolic dysfunction-associated steatotic liver disease
(MASLD) is significantly higher in men versus women. Increased prevalence is observed in …
(MASLD) is significantly higher in men versus women. Increased prevalence is observed in …
Fatty Liver Index (FLI) is the best score to predict MASLD with 50% lower cut-off value in women than in men
L Crudele, C De Matteis, F Novielli, E Di Buduo… - Biology of sex …, 2024 - Springer
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined by
the presence of hepatic steatosis, detected on ultrasonography (US) imaging or histology …
the presence of hepatic steatosis, detected on ultrasonography (US) imaging or histology …
Effective anti-tumor immune responses are orchestrated by immune cell partnership network that functions through tissue homeostatic pathways, not direct cytotoxicity
N Koelsch, F Mirshahi, HF Aqbi, M Seneshaw… - bioRxiv, 2024 - biorxiv.org
The liver hosts a diverse array of immune cells that play pivotal roles in both maintaining
tissue homeostasis and responding to disease. However, the precise contributions of these …
tissue homeostasis and responding to disease. However, the precise contributions of these …
Immune cell balance as potential biomarker of progressing non-alcoholic fatty liver disease
LV Topchieva, IV Kurbatova, OP Dudanova… - Genes & Cells, 2024 - genescells.ru
Nonalcoholic fatty liver disease (NAFLD) is a widespread chronic, slowly progressive
metabolic multifactorial disease. It is represented by several clinical and morphological …
metabolic multifactorial disease. It is represented by several clinical and morphological …