Fear memory

I Izquierdo, CRG Furini, JC Myskiw - Physiological reviews, 2016 - journals.physiology.org
Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

Re-evaluating circuit mechanisms underlying pattern separation

NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …

[HTML][HTML] A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI

JE Iglesias, JC Augustinack, K Nguyen, CM Player… - Neuroimage, 2015 - Elsevier
Automated analysis of MRI data of the subregions of the hippocampus requires
computational atlases built at a higher resolution than those that are typically used in current …

Optogenetic stimulation of a hippocampal engram activates fear memory recall

X Liu, S Ramirez, PT Pang, CB Puryear… - Nature, 2012 - nature.com
A specific memory is thought to be encoded by a sparse population of neurons,. These
neurons can be tagged during learning for subsequent identification and manipulation …

A computational theory of hippocampal function, and tests of the theory: new developments

RP Kesner, ET Rolls - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …

All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis

C Vivar, MC Potter, H van Praag - Neurogenesis and neural plasticity, 2013 - Springer
Accumulating evidence from animal and human research shows exercise benefits learning
and memory, which may reduce the risk of neurodegenerative diseases, and could delay …

Hippocampal somatostatin interneurons control the size of neuronal memory ensembles

T Stefanelli, C Bertollini, C Lüscher, D Muller… - Neuron, 2016 - cell.com
Hippocampal neurons activated during encoding drive the recall of contextual fear memory.
Little is known about how such ensembles emerge during acquisition and eventually form …

Vitamin A and retinoic acid in cognition and cognitive disease

MU Wołoszynowska-Fraser… - Annual review of …, 2020 - annualreviews.org
The history of vitamin A goes back over one hundred years, but our realization of its
importance for the brain and cognition is much more recent. The brain is more efficient than …

Adult hippocampal neurogenesis, fear generalization, and stress

A Besnard, A Sahay - Neuropsychopharmacology, 2016 - nature.com
The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …

The human dentate gyrus plays a necessary role in discriminating new memories

S Baker, P Vieweg, F Gao, A Gilboa, T Wolbers… - Current Biology, 2016 - cell.com
Our day-to-day experiences are often similar to one another, occurring in the same place at
the same time of day, with common people and objects, and with a shared purpose. Humans …