Cannabis use and cannabis use disorder

JP Connor, D Stjepanović, B Le Foll, E Hoch… - Nature Reviews …, 2021 - nature.com
Cannabis use disorder (CUD) is an underappreciated risk of using cannabis that affects~
10% of the 193 million cannabis users worldwide. The individual and public health burdens …

Evidence for the risks and consequences of adolescent cannabis exposure

A Levine, K Clemenza, M Rynn, J Lieberman - Journal of the American …, 2017 - Elsevier
Objective This review of the scientific literature examines the potential adult sequelae of
exposure to cannabis and related synthetic cannabinoids in adolescence. We examine the …

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

DF Levey, M Galimberti, JD Deak, FR Wendt… - Nature Genetics, 2023 - nature.com
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …

A large-scale genome-wide association study meta-analysis of cannabis use disorder

EC Johnson, D Demontis, TE Thorgeirsson… - The Lancet …, 2020 - thelancet.com
Background Variation in liability to cannabis use disorder has a strong genetic component
(estimated twin and family heritability about 50–70%) and is associated with negative …

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

JA Pasman, KJH Verweij, Z Gerring, S Stringer… - Nature …, 2018 - nature.com
Cannabis use is a heritable trait that has been associated with adverse mental health
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …

[图书][B] Behavioral genetics

R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

The genetic epidemiology of substance use disorder: A review

EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

The genetics of addiction—a translational perspective

A Agrawal, KJH Verweij, NA Gillespie, AC Heath… - Translational …, 2012 - nature.com
Addictions are serious and common psychiatric disorders, and are among the leading
contributors to preventable death. This selective review outlines and highlights the need for …

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

S Stringer, CC Minică, KJH Verweij, H Mbarek… - Translational …, 2016 - nature.com
Cannabis is the most widely produced and consumed illicit psychoactive substance
worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence …

[HTML][HTML] Predicting the transition from frequent cannabis use to cannabis dependence: a three-year prospective study

P Van Der Pol, N Liebregts, R De Graaf, DJ Korf… - Drug and alcohol …, 2013 - Elsevier
Background Frequent cannabis users are at high risk of dependence, still most (near) daily
users are not dependent. It is unknown why some frequent users develop dependence …