The role of inflammation in venous thromboembolism

BR Branchford, SL Carpenter - Frontiers in pediatrics, 2018 - frontiersin.org
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT), and pulmonary
embolism (PE), is becoming increasingly recognized as a cause of morbidity and mortality in …

Platelets: bridging hemostasis, inflammation, and immunity

CN Jenne, R Urrutia, P Kubes - International journal of …, 2013 - Wiley Online Library
Although the function of platelets in the maintenance of hemostasis has been studied in
great detail, more recent evidence has highlighted a central role for platelets in the host …

Blood coagulation in immunothrombosis—at the frontline of intravascular immunity

F Gaertner, S Massberg - Seminars in immunology, 2016 - Elsevier
While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

CHY Wong, CN Jenne, B Petri, NL Chrobok… - Nature …, 2013 - nature.com
Through the use of intravital imaging of the liver, we demonstrate a collaborative role for
platelets with Kupffer cells (KCs) in eradicating blood-borne bacterial infection. Under basal …

[HTML][HTML] Platelets in inflammation and immunity

JM Herter, J Rossaint, A Zarbock - Journal of Thrombosis and Haemostasis, 2014 - Elsevier
The paradigm of platelets as mere mediators of hemostasis has long since been replaced by
a dual role: hemostasis and inflammation. Now recognized as key players in innate and …

Mechanisms of blood brain barrier disruption by different types of bacteria, and bacterial–host interactions facilitate the bacterial pathogen invading the brain

MMJ Al-Obaidi, MNM Desa - Cellular and molecular neurobiology, 2018 - Springer
This review aims to elucidate the different mechanisms of blood brain barrier (BBB)
disruption that may occur due to invasion by different types of bacteria, as well as to show …

Immunohaemostasis: a new view on haemostasis during sepsis

X Delabranche, J Helms, F Meziani - Annals of intensive care, 2017 - Springer
Host infection by a micro-organism triggers systemic inflammation, innate immunity and
complement pathways, but also haemostasis activation. The role of thrombin and fibrin …

Bacteria pattern spontaneously on periodic nanostructure arrays

AI Hochbaum, J Aizenberg - Nano letters, 2010 - ACS Publications
Surface-associated bacteria typically form self-organizing communities called biofilms.
Spatial segregation is important for various bacterial processes associated with cellular and …

[HTML][HTML] Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability

JQ Boedicker, ME Vincent… - … Chemie (International ed …, 2009 - ncbi.nlm.nih.gov
Herein we show that upon confinement in small volumes, groups of Pseudomonas
aeruginosa bacteria, containing as few as one to three cells, are able to initiate quorum …

Microfluidics expanding the frontiers of microbial ecology

R Rusconi, M Garren, R Stocker - Annual review of biophysics, 2014 - annualreviews.org
Microfluidics has significantly contributed to the expansion of the frontiers of microbial
ecology over the past decade by allowing researchers to observe the behaviors of microbes …