Invasive brain–machine interfaces can restore motor, sensory and cognitive functions.
However, their clinical adoption has been hindered by the surgical risk of implantation and …

Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

To ensure long-term consistent neural recordings, next-generation intracortical
microelectrodes are being developed with an increased emphasis on reducing the neuro …

Many studies over the past two decades have shown that people and animals can use brain
signals to convey their intent to a computer using brain-computer interfaces (BCIs). BCI …

Implantable neural interfaces for central nervous system research have been designed with
wire, polymer, or micromachining technologies over the past 70 years. Research on …

For nearly 55 years, tungsten microwires have been widely used in neurophysiological
experiments in animal models to chronically record neuronal activity. While tungsten …

Chronically implanted neural multi-electrode arrays (MEA) are an essential technology for
recording electrical signals from neurons and/or modulating neural activity through …

Glial scar is a significant barrier to neural implant function. Micromotion between the implant
and tissue is suspected to be a key driver of glial scar formation around neural implants. This …

This review intends to present a comprehensive analysis of the mechanical considerations
for chronically-implanted neural probes. Failure of neural electrical recordings or stimulation …