Monoclonal antibody therapies against SARS-CoV-2

D Focosi, S McConnell, A Casadevall… - The Lancet Infectious …, 2022 - thelancet.com
Monoclonal antibodies (mAbs) targeting the spike protein of SARS-CoV-2 have been widely
used in the ongoing COVID-19 pandemic. In this paper, we review the properties of mAbs …

Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence

D Focosi, F Maggi, A Casadevall - Viruses, 2022 - mdpi.com
Sterilizing immunity after vaccination is desirable to prevent the spread of infection from
vaccinees, which can be especially dangerous in hospital settings while managing frail …

Prophylaxis against covid-19: living systematic review and network meta-analysis

JJ Bartoszko, RAC Siemieniuk, E Kum, A Qasim… - Bmj, 2021 - bmj.com
Updates This is the second version (first update) of the living systematic review, replacing
the previous version (available as a data supplement). When citing this paper please …

COVID-19 at a glance: An up-to-date overview on variants, drug design and therapies

D Iacopetta, J Ceramella, A Catalano, C Saturnino… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the
Coronavirus family which caused the worldwide pandemic of human respiratory illness …

Polyclonal anti-whole cell IgY passive immunotherapy shields against P. aeruginosa-induced acute pneumonia and burn wound infections in murine models

TS Ahmadi, B Behrouz, SL Mousavi Gargari - Scientific Reports, 2024 - nature.com
Pseudomonas aeruginosa (PA) is a multidrug-resistant (MDR) opportunistic pathogen
causing severe hospital-, and community-acquired infections worldwide. Thus, the …

Trends in industrialization and commercialization of IgY technology

S Yakhkeshi, R Wu, B Chelliappan… - Frontiers in …, 2022 - frontiersin.org
IgY technology refers to the strategic production process involved in generating avian
immunoglobulin (IgY) against target antigens in a much more cost-effective manner with …

Egg yolk antibody for passive immunization: status, challenges, and prospects

H Wang, Q Zhong, J Lin - Journal of Agricultural and Food …, 2023 - ACS Publications
The immunoglobulin Y (IgY) derived from hyperimmune egg yolk is a promising passive
immune agent to combat microbial infections in humans and livestock. Numerous studies …

Respiratory delivery of passive immunotherapies for SARS-CoV-2 prophylaxis and therapy

D Focosi, F Maggi - Human Vaccines & Immunotherapeutics, 2023 - Taylor & Francis
Convalescent plasma has been extensively tested during the COVID-19 pandemic as a
transfusion product. Similarly, monoclonal antibodies have been largely administered either …

Are hamsters a suitable model for evaluating the immunogenicity of RBD-based anti-COVID-19 subunit vaccines?

IA Merkuleva, DN Shcherbakov, MB Borgoyakova… - Viruses, 2022 - mdpi.com
Currently, SARS-CoV-2 spike receptor-binding-domain (RBD)-based vaccines are
considered one of the most effective weapons against COVID-19. During the first step of …

[HTML][HTML] Passive immunization with anti-FimA egg yolk antibodies (IgYs) mitigate Acinetobacter baumannii pneumonia in mice

N Shaygankho, A Jahangiri, I Rasooli - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Acinetobacter baumannii is a formidable pathogen, characterized by high mortality rates and
pan-drug-resistant strains. Current commercial antibiotics lack efficacy against drug-resistant …