Molecular mechanism of doxorubicin-induced cardiomyopathy–An update
Doxorubicin is utilized for anti-neoplastic treatment for several decades. The utility of this
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …
Doxorubicin-induced cardiotoxicity: an overview on pre-clinical therapeutic approaches
Doxorubicin is an effective chemotherapeutic agent prescribed to treat solid tumors (eg,
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …
Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
Background Doxorubicin (DOX) is commonly used in the treatment of many types of cancers
but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin …
but its cardiotoxicity is limiting its clinical use. Beyond its anticoagulant action, enoxaparin …
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products
Background As an anthracycline antibiotic, doxorubicin (DOX) is one of the most potent and
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …
Oxidative stress and inflammation: determinants of anthracycline cardiotoxicity and possible therapeutic targets
Chemotherapy with anthracycline-based regimens remains a cornerstone of treatment of
many solid and blood tumors but is associated with a significant risk of cardiotoxicity, which …
many solid and blood tumors but is associated with a significant risk of cardiotoxicity, which …
Wheat phenolics suppress doxorubicin-induced cardiotoxicity via inhibition of oxidative stress, MAP kinase activation, NF-κB pathway, PI3K/Akt/mTOR impairment …
The present investigation has been undertaken to reveal the protective mechanism of
polyphenolics extract of whole wheat grains (WWGPE), ferulic acid and apigenin against …
polyphenolics extract of whole wheat grains (WWGPE), ferulic acid and apigenin against …
Toxic effects and molecular mechanism of doxorubicin on different organs–an update
K Renu, LP Pureti, B Vellingiri… - Toxin …, 2022 - Taylor & Francis
Doxorubicin is an extensively used anti-neoplastic drug used for solid and hematogenous
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …
Liposomal resveratrol and/or carvedilol attenuate doxorubicin-induced cardiotoxicity by modulating inflammation, oxidative stress and S100A1 in rats
AM Alanazi, L Fadda, A Alhusaini, R Ahmad, IH Hasan… - Antioxidants, 2020 - mdpi.com
Doxorubicin (DOX) is a cytotoxic anthracycline antibiotic and one of the important
chemotherapeutic agents for different types of cancers. DOX treatment is associated with …
chemotherapeutic agents for different types of cancers. DOX treatment is associated with …
[HTML][HTML] Molecular mechanisms of endothelial remodeling under doxorubicin treatment
E Podyacheva, M Danilchuk, Y Toropova - Biomedicine & …, 2023 - Elsevier
Doxorubicin (DOX) is an effective antineoplastic agent used to treat various types of cancers.
However, its use is limited by the development of cardiotoxicity, which may result in heart …
However, its use is limited by the development of cardiotoxicity, which may result in heart …
Date palm pollen extract avert doxorubicin-induced cardiomyopathy fibrosis and associated oxidative/nitrosative stress, inflammatory cascade, and apoptosis …
Simple Summary The use of date palm pollen ethanolic extract (DPPE) is a conventional
approach in improving the side-effects induced by Doxorubicin (DOX). DPPE mitigated DOX …
approach in improving the side-effects induced by Doxorubicin (DOX). DPPE mitigated DOX …