Self-emulsifying drug delivery systems: An alternative approach to improve brain bioavailability of poorly water-soluble drugs through intranasal administration
S Meirinho, M Rodrigues, AO Santos, A Falcão… - Pharmaceutics, 2022 - mdpi.com
Efforts in discovering new and effective neurotherapeutics are made daily, although most fail
to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous …
to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous …
Exploring the role of self-nanoemulsifying systems in drug delivery: challenges, issues, applications and recent advances
Nanotechnology has attracted researchers around the globe owing to the small size and
targeting properties of the drug delivery vectors. The interest in self-nanoemulsifying drug …
targeting properties of the drug delivery vectors. The interest in self-nanoemulsifying drug …
3D printing of dapagliflozin containing self-nanoemulsifying tablets: Formulation design and in vitro characterization
The 3D printing techniques have been explored extensively in recent years for
pharmaceutical manufacturing and drug delivery applications. The current investigation …
pharmaceutical manufacturing and drug delivery applications. The current investigation …
Famotidine-loaded solid self-nanoemulsifying drug delivery system demonstrates exceptional efficiency in amelioration of peptic ulcer
WA El-Dakroury, MB Zewail, M Elsabahy… - International Journal of …, 2022 - Elsevier
Famotidine (FMD) is a highly potent H 2-receptor antagonist used in peptic ulcer treatment.
However, the drug possesses poor aqueous solubility and permeability. FMD-loaded solid …
However, the drug possesses poor aqueous solubility and permeability. FMD-loaded solid …
The enhanced pH-dependent solubility behavior of three novel lamotrigine-acid salts
J Li, Y Zhu, C Zhang, D Yang, Y Lu, Z Zhou - Journal of Molecular Liquids, 2023 - Elsevier
Abstract Lamotrigine (LAM), a Biopharmaceutics Classification System (BCS) class II drug, is
widely used to treat epilepsy, bipolar disorder and neuropathic pain. However, its low …
widely used to treat epilepsy, bipolar disorder and neuropathic pain. However, its low …
Development and exploration on flowability of solid self-nanoemulsifying drug delivery system of morin hydrate
Morin hydrate (MH) is a promising flavonoid with diverse biological activities; unfortunately, it
finds limited clinical application due to its low water solubility. Herein, we developed a liquid …
finds limited clinical application due to its low water solubility. Herein, we developed a liquid …
Cubosome-based thermosensitive in situ gelling system for intranasal administration of lamotrigine with enhanced antiepileptic efficacy
AM Mohsen, AAA Salama… - Pharmaceutical …, 2023 - Taylor & Francis
Lamotrigine (LTG) is a second-generation antiepileptic drug that belongs to
Biopharmaceutics Classification System (BCS) class II. LTG has a low probability of crossing …
Biopharmaceutics Classification System (BCS) class II. LTG has a low probability of crossing …
SEDDS basic design and recent formulation advancement: a concurrent review
KC Panigrahi, CN Patra, MEB Rao… - Pharmaceutical …, 2022 - ingentaconnect.com
In the present scenario, lipid-based novel drug delivery systems are the area of interest for
the formulation scientist in order to improve the bioavailability of poorly water-soluble drugs …
the formulation scientist in order to improve the bioavailability of poorly water-soluble drugs …
Genetics of Dravet Syndrome and Its Targeted Therapy by Nanomedicine: A Roadmap for Future Treatment of Drug Resistant Seizures
According to the World Health Organization (WHO), epilepsy is the 4th most prevalent
neurological disorder after migraine, stroke, and Alzheimer's disease. There are numerous …
neurological disorder after migraine, stroke, and Alzheimer's disease. There are numerous …
Pharmaceutical Modifications of Capsaicin to Enhance its Bioavailability
M Prashar, N Dhingra, S Raj - … : From Natural Sources to Biosynthesis and …, 2024 - Springer
Abstract Capsaicin or N-vanillyl-8-methyl-6-(E)-none amide, a unique key constituent from
the Capsicum genus, is a pharmaceutical agent with a wide range of therapeutic …
the Capsicum genus, is a pharmaceutical agent with a wide range of therapeutic …