Inflammatory bowel diseases (IBDs) are chronic immune-mediated conditions characterized
by significant gut tissue damage due to uncontrolled inflammation. Anti-inflammatory …

Inflammation is a physiological condition characterized by a complex interplay between
different cells handled by metabolites and specific inflammatory-related molecules. In some …

Inflammatory bowel diseases are characterized by the chronic relapsing inflammation of the
gastrointestinal tract. While the molecular causality between endoplasmic reticulum (ER) …

Background ERAP2 is an aminopeptidase involved in antigen processing and presentation,
and harbor genetic variants linked to several inflammatory diseases such as Inflammatory …

Background & Aims Fibrosis development in ulcerative colitis is associated directly with the
severity of mucosal inflammation, which increases the risk of colorectal cancer. The …

Crohn's disease (CD) is a complex and heterogeneous condition with no perfect preclinical
model or cure. To address this, we explore adult stem cell-derived organoids that retain their …

Ethnopharmacological relevance Diabetic ulcer is a serious diabetes complication and a
primary reason for amputations. For many years, the San Huang Xiao Yan (SHXY) recipe …

Perianal fistulizing Crohn's disease (CD) is a severe gastrointestinal disorder causing
extensive mucosal damage with limited treatment options. Severe manifestations of the …

ABSTRACT Background and Aims Irritable bowel syndrome (IBS), inflammatory bowel
disease (IBD), and celiac disease (CeD) present with similar gastrointestinal (GI) symptoms …

Microbiota and luminal components may affect epithelial integrity and thus participate in the
pathophysiology of colon cancer (CC) and inflammatory bowel disease (IBD). Therefore, we …