Leukemia is developed following the abnormal proliferation of immature hematopoietic cells
in the blood when hematopoietic stem cells lose the ability to turn into mature cells at …

Background Bone marrow stromal cells (BMSCs) are known to promote chemoresistance in
acute myeloid leukemia (AML) cells. However, the molecular basis for BMSC-associated …

Osteopontin (OPN) is a glycoprotein involved in regulation of various influences on tumor
progression, such as cellular proliferation, apoptosis, angiogenesis, and metastasis …

A wound is the pathological change of soft tissue under normal skin caused by various
factors, such as collision, contusion, hot crush, avulsion, corrosive chemicals, operations …

Acute myeloid leukemias (AMLs) are blood disorders that exhibit uncontrolled growth and
reduction of apoptosis rates. As with other malignancies, progression may be result of …

Despite impressive advances in therapeutic approaches, long-term survival with acute
myeloid leukemia (AML) is low as a result of treatment resistance and frequent relapse …

Acute myeloid leukemia (AML) is a blood disorder characterized by uncontrolled
proliferation of myeloid progenitors and decrease in the apoptosis rate. The vascular …

Acute myeloid leukemia (AML), is a clonal disorder caused by acquired somatic mutations
and chromosomal rearrangements. According to some evidence, progression of …

Bone marrow‑derived mesenchymal stem cells (MSCs), are the basic cellular components
that make up the bone marrow microenvironment (BMM). In acute myeloid leukemia (AML) …

Osteopontin (OPN) is an extracellular structural protein that is secreted by osteoblasts and
hematopoietic cells. It suppresses the proliferation of hematopoietic stem and also plays an …