Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of
hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A …

Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Summary The Standards of Care Committee of the British Society for Allergy and Clinical
Immunology (BSACI) and an expert panel have prepared this guidance for the management …

Adverse drug reactions (ADRs) result in major health problems in the United States in both
the inpatient and outpatient setting. ADRs are broadly categorized into predictable (type A …

BACKGROUND: The practice of avoiding cephalosporin administration to penicillin-allergic
patients persists despite the low rate of cross reactions between both groups of antibiotics …

The American Academy of Pediatrics, evidence-based guidelines endorse the use of
cephalosporin antibiotics for patients with reported allergies to penicillin, for the treatment of …

Background: Penicillin is no longer the most commonly prescribed β‐lactam, and the pattern
of reactions has changed. We studied the diagnostic value of skin testing in penicillin …

Background Having a penicillin allergy label associates with a higher risk for antibiotic
resistance and increased health care use. Objective We sought to assess the accuracy of …

Background Recent analysis of clinical data and a clearer understanding of the role of
chemical structure in the development of cross-reactivity indicate that the increased risk of …