Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Aptamers chemistry: Chemical modifications and conjugation strategies

F Odeh, H Nsairat, W Alshaer, MA Ismail, E Esawi… - Molecules, 2019 - mdpi.com
Soon after they were first described in 1990, aptamers were largely recognized as a new
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …

Structure–relaxivity relationships of magnetic nanoparticles for magnetic resonance imaging

Z Zhou, L Yang, J Gao, X Chen - Advanced Materials, 2019 - Wiley Online Library
Magnetic nanoparticles (MNPs) have been extensively explored as magnetic resonance
imaging (MRI) contrast agents. With the increasing complexity in the structure of modern …

Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives

ES Ali, SM Sharker, MT Islam, IN Khan, S Shaw… - Seminars in cancer …, 2021 - Elsevier
Nanotechnology is reshaping health care strategies and is expected to exert a tremendous
impact in the coming years offering better healthcare facilities. It has led to not only …

Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy

J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

(Intra) cellular stability of inorganic nanoparticles: effects on cytotoxicity, particle functionality, and biomedical applications

SJ Soenen, WJ Parak, J Rejman, B Manshian - Chemical reviews, 2015 - ACS Publications
In recent years, the growth in the field of nanotechnology has stimulated many other areas,
which eventually may involve everyday life uses as well as high-tech biomedical …

Hybrid nanoparticles for detection and treatment of cancer

MJ Sailor, JH Park - Advanced materials, 2012 - Wiley Online Library
There is currently considerable effort to incorporate both diagnostic and therapeutic
functions into a single nanoscale system for the more effective treatment of cancer …

Self-assembled plasmonic vesicles of SERS-encoded amphiphilic gold nanoparticles for cancer cell targeting and traceable intracellular drug delivery

J Song, J Zhou, H Duan - Journal of the American Chemical …, 2012 - ACS Publications
We report the development of bioconjugated plasmonic vesicles assembled from SERS-
encoded amphiphilic gold nanoparticles for cancer-targeted drug delivery. This new type of …

Aptamer-guided nanomedicines for anticancer drug delivery

W Alshaer, H Hillaireau, E Fattal - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …

Enhancement of photodynamic cancer therapy by physical and chemical factors

M Yang, T Yang, C Mao - Angewandte Chemie International …, 2019 - Wiley Online Library
The viable use of photodynamic therapy (PDT) in cancer therapy has never been fully
realized because of its undesirable effects on healthy tissues. Herein we summarize some …