It is often thought that the construction of cortical circuits occurs as the result of an elegantly
designed process that unfolds sequentially as an animal develops until adult functional …

The generation of new neurons in the adult brain is a currently accepted phenomenon. Over
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …

Hippocampome. org is a mature open-access knowledge base of the rodent hippocampal
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …

Neurogenesis is a powerful mechanism for structural and functional remodeling that occurs
in restricted areas of the adult brain. Although different neurotransmitters regulate various …

Post-traumatic epilepsy (PTE) and behavioral comorbidities frequently develop after
traumatic brain injury (TBI). Aberrant neurogenesis of dentate granule cells (DGCs) after TBI …

The nucleus accumbens (NAc) is a crucial region in the reward circuit and is related to
anhedonia, the pivotal symptom of major depression disorder (MDD). Deep brain stimulation …

Adult-born granule cells (abGCs) exhibit a transient period of elevated synaptic plasticity that
plays an important role in hippocampal function. Various mechanisms have been implicated …

The extracellular matrix (ECM) of the brain plays a crucial role in providing optimal
conditions for neuronal function. Interactions between neurons and a specialized form of …

Hilar mossy cells regulate network function in the hippocampus through both direct
excitation and di-synaptic inhibition of dentate granule cells (DGCs). Substantial mossy cell …

GABAergic inhibition is critical for the precision of neuronal spiking and the homeostatic
regulation of network activity in the brain. Adult neurogenesis challenges network …