Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …

Quantitative sensory testing (QST) is a psychophysical method used to quantify
somatosensory function in response to controlled stimuli in healthy subjects and patients …

Neuropathic pain is triggered by lesions to the somatosensory nervous system that alter its
structure and function so that pain occurs spontaneously and responses to noxious and …

Peripheral neuropathic pain is produced by multiple etiological factors that initiate a number
of diverse mechanisms operating at different sites and at different times and expressed both …

Many are frustrated with the lack of translational progress in the pain field, in which huge
gains in basic science knowledge obtained using animal models have not led to the …

Pain: Moving from Symptom Control toward Mechanism-Specific Pharmacologic
Management | Annals of Internal Medicine Advertisement ACP Online Annals of Internal …

Neuroimmune diseases have diverse symptoms and etiologies but all involve pathological
inflammation that affects normal central nervous system signaling. Critically, many …

Objective: This assessment evaluates the clinical utility, efficacy, and safety of quantitative
sensory testing (QST). Methods: By searching MEDLINE, Current Contents, and their …