Antibody tests for identification of current and past infection with SARS‐CoV‐2
Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection
The immune response to SARS-CoV-2 is critical in controlling disease, but there is concern
that waning immunity may predispose to reinfection. We analyzed the magnitude and …
that waning immunity may predispose to reinfection. We analyzed the magnitude and …
Delayed production of neutralizing antibodies correlates with fatal COVID-19
Recent studies have provided insights into innate and adaptive immune dynamics in
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …
[HTML][HTML] SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2
F Amanat, M Thapa, T Lei, SMS Ahmed, DC Adelsberg… - Cell, 2021 - cell.com
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
[HTML][HTML] Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses
Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual
characteristics influencing it, including the impact of pre-existing antibodies to human …
characteristics influencing it, including the impact of pre-existing antibodies to human …
[HTML][HTML] Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …
respiratory distress and death. A major unresolved question is whether prior immunity to …
Lack of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a large cohort of previously infected persons
LR Petersen, S Sami, N Vuong… - Clinical Infectious …, 2021 - academic.oup.com
Background Reports suggest that some persons previously infected with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) lack detectable immunoglobulin G (IgG) …
respiratory syndrome coronavirus 2 (SARS-CoV-2) lack detectable immunoglobulin G (IgG) …
[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …
instigating devastating effects on the global health care system whose impacts could be …
The role of B cells in COVID-19 infection and vaccination
S Chen, F Guan, F Candotti, K Benlagha… - Frontiers in …, 2022 - frontiersin.org
B cells secrete antibodies and mediate the humoral immune response, making them
extremely important in protective immunity against SARS-CoV-2, which caused the …
extremely important in protective immunity against SARS-CoV-2, which caused the …