Endophytic fungi: Key insights, emerging prospects, and challenges in natural product drug discovery

P Tiwari, H Bae - Microorganisms, 2022 - mdpi.com
Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

Endophytic fungi: biodiversity, ecological significance, and potential industrial applications

KL Rana, D Kour, I Sheikh, A Dhiman, N Yadav… - Recent advancement in …, 2019 - Springer
Endophytic fungi are abundant and have been reported from all tissues such as roots,
stems, leaves, flowers, and fruits. In recent years, research into the beneficial use of …

Endophytes as in vitro production platforms of high value plant secondary metabolites

A Venugopalan, S Srivastava - Biotechnology advances, 2015 - Elsevier
Many reports have been published on bioprospecting of endophytic fungi capable of
producing high value bioactive molecules like, paclitaxel, vincristine, vinblastine …

Plant bioactive metabolites and drugs produced by endophytic fungi of Spermatophyta

R Nicoletti, A Fiorentino - Agriculture, 2015 - mdpi.com
It is known that plant-based ethnomedicine represented the foundation of modern
pharmacology and that many pharmaceuticals are derived from compounds occurring in …

[HTML][HTML] Plant-endophyte associations: Rich yet under-explored sources of novel bioactive molecules and applications

P Tiwari, S Kang, H Bae - Microbiological Research, 2023 - Elsevier
Diverse forms of plant-microbe associations affect agriculture and the environment. Both
plants and microbes have evolved to produce a variety of proteins and metabolites to enable …

Endophytic fungi residing in medicinal plants have the ability to produce the same or similar pharmacologically active secondary metabolites as their hosts

A Venieraki, M Dimou, P Katinakis - Hellenic Plant Protection Journal, 2017 - sciendo.com
Medicinal plants have been used for thousands of years in folk medicines and still are used
for their health benefits. In our days medicinal plants are exploited for the isolation of plant …

Characterization of the Plant Growth-Promoting Activities of Endophytic Fungi Isolated from Sophora flavescens

A Turbat, D Rakk, A Vigneshwari, S Kocsubé, H Thu… - Microorganisms, 2020 - mdpi.com
Endophytic fungi in symbiotic association with their host plant are well known to improve
plant growth and reduce the adverse effects of both biotic and abiotic stresses. Therefore …

Diversity and bioactive potential of culturable fungal endophytes of Dysosma versipellis; a rare medicinal plant endemic to China

X Tan, Y Zhou, X Zhou, X Xia, Y Wei, L He, H Tang… - Scientific Reports, 2018 - nature.com
The plant Dysosma versipellis is known for its antimicrobial and anticancer properties but is
a rare and vulnerable perennial herb that is endemic to China. In this study, 224 isolates …

Prospecting potential of endophytes for modulation of biosynthesis of therapeutic bioactive secondary metabolites and plant growth promotion of medicinal and …

D Singh, S Thapa, H Mahawar, D Kumar… - Antonie Van …, 2022 - Springer
Medicinal and aromatic plants possess pharmacological properties (antidiabetes,
anticancer, antihypertension, anticardiovascular, antileprosy, etc.) because of their potential …