The coagulation and immune systems, two vital systems in the human body, share intimate
connections that fundamentally determine patient health. These systems work together …

Disseminated intravascular coagulation (DIC) is a recurrent complication of sepsis. Since
DIC not only promotes organ dysfunction but also represents a strong prognostic factor, it is …

Background Vitamin K is essential for numerous physiological processes, including
coagulation, bone metabolism, tissue calcification, and antioxidant activity. Deficiency …

Background This study aimed to explore the hemostatic profile of neonates with necrotizing
enterocolitis (NEC) using Rotational Thromboelastometry (ROTEM) and to investigate if …

Severe hemostatic disturbances and impaired fibrinolysis occur in sepsis. In the most
serious cases, the dysregulation of fibrinolysis contributes to septic shock, disseminated …

Molecular Pathways in Sepsis Pathogenesis: Recent Advances and Therapeutic Avenues
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Background Sepsis is a complex condition characterized by systemic host inflammation
caused by an infection. Experimental and observational studies indicate that obesity, one of …

The assessment of hemostatic disorders in neonates is crucial, but remains challenging for
clinicians. Although the concept of developmental hemostasis is widely accepted among …

Background Sepsis is a life-threatening disease commonly complicated by activation of
coagulation and immune pathways. Sepsis-induced coagulopathy (SIC) is associated with …

Introduction This study aimed at evaluating the role of rotational thromboelastometry
(ROTEM) assays in the prediction of in‐hospital mortality of neonates with sepsis. Methods …