Ion channels in lung cancer: biological and clinical relevance
C Capitani, G Chioccioli Altadonna… - Frontiers in …, 2023 - frontiersin.org
Despite improvements in treatment, lung cancer is still a major health problem worldwide.
Among lung cancer subtypes, the most frequent is represented by adenocarcinoma …
Among lung cancer subtypes, the most frequent is represented by adenocarcinoma …
Targeting the hERG1 and β1 integrin complex for cancer treatment
A Arcangeli, J Iorio, C Duranti - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
Introduction Despite great advances, novel therapeutic targets and strategies are still
needed, in particular for some carcinomas in the metastatic stage (breast cancer, colorectal …
needed, in particular for some carcinomas in the metastatic stage (breast cancer, colorectal …
Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells
C Duranti, J Iorio, G Bagni, GC Altadonna… - Life science …, 2024 - life-science-alliance.org
The hERG1 potassium channel is aberrantly over expressed in tumors and regulates the
cancer cell response to integrin-dependent adhesion. We unravel a novel signaling pathway …
cancer cell response to integrin-dependent adhesion. We unravel a novel signaling pathway …
The role of potassium channels in tumours of the gastrointestinal tract: a focus on the human ether‐à‐go‐go related gene 1 channels
A Arcangeli, C Duranti, J Iorio… - The Journal of …, 2023 - Wiley Online Library
Potassium channels are often dysregulated in tumours of the gastrointestinal (GI) tract.
Among them, the voltage‐dependent channel KV11. 1, also known as human ether‐à‐go …
Among them, the voltage‐dependent channel KV11. 1, also known as human ether‐à‐go …
[HTML][HTML] Effects of Germanium embedded fabric on the chondrogenic differentiation of adipose derived stem cells
C Duranti, G Bagni, J Iorio, R Colasurdo, V Devescovi… - Tissue and Cell, 2024 - Elsevier
Osteoarthritis (OA) is a clinical state which is identified by the degeneration of articular
cartilage. OA is a common condition (> 500 millions of people affected worldwide), whose …
cartilage. OA is a common condition (> 500 millions of people affected worldwide), whose …
Combination therapy with a bispecific antibody targeting the hERG1/β1 integrin complex and gemcitabine in pancreatic ductal adenocarcinoma
T Lottini, C Duranti, J Iorio, M Martinelli, R Colasurdo… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers
and is forecasted to become the second most common cause of cancer-related deaths by …
and is forecasted to become the second most common cause of cancer-related deaths by …