The surface of all living cells is decorated with carbohydrate molecules. Hundreds of
functional proteins bind to these glycosylated ligands; such binding events subsequently …

The glycocalyx attached to the apical surface of vascular endothelial cells is a rich network
of proteoglycans, glycosaminoglycans, and glycoproteins with instrumental roles in vascular …

Glycosaminoglycans (GAGs) are long, linear polysaccharides that are ubiquitously
expressed on the cell surface and in the extracellular matrix of all animal cells. These …

Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection triggers various
events from molecular to tissue level, which in turn is given by the intrinsic characteristics of …

Heparin, a highly sulfated glycosaminoglycan, is considered an indispensable anticoagulant
with diverse therapeutic applications and has been a mainstay in medical practice for nearly …

Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan
sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are …

Heparan sulfate (HS) proteoglycans bind extracellular proteins that participate in cell
signaling, attachment and endocytosis. These interactions depend on the arrangement of …

The functions of non-coding regulatory elements (NCREs), which constitute a major fraction
of the human genome, have not been systematically studied. Here we report a method …

Introduction Dysregulated inflammation and coagulation are underlying mechanisms driving
organ injury after trauma and hemorrhagic shock. Heparan sulfates, cell surface …

Frugivory evolved multiple times in mammals, including bats. However, the cellular and
molecular components driving it remain largely unknown. Here, we use integrative single …