Elastic fibers in the intervertebral disc: From form to function and toward regeneration

D Cyril, A Giugni, SS Bangar… - International Journal of …, 2022 - mdpi.com
Despite extensive efforts over the past 40 years, there is still a significant gap in knowledge
of the characteristics of elastic fibers in the intervertebral disc (IVD). More studies are …

Recent progress in strain-engineered stretchable constructs

A Hanif, D Yoo, D Kim, F Mustafayev, S Hajiyev… - International Journal of …, 2024 - Springer
A variety of natural biological tissues (eg, skin, ligaments, and blood vessels) exhibit a J-
shaped stress–strain behavior, combining soft, compliant mechanics and large levels of …

[HTML][HTML] On the characteristics of natural hydraulic dampers: An image-based approach to study the fluid flow behaviour inside the human meniscal tissue

J Waghorne, FP Bonomo, A Rabbani, D Bell, O Barrera - Acta Biomaterialia, 2024 - Elsevier
The meniscal tissue is a layered material with varying properties influenced by collagen
content and arrangement. Understanding the relationship between structure and properties …

The mechanical behavior of silk-fibroin reinforced alginate hydrogel biocomposites-Toward functional tissue biomimetics

A Aharonov, HS Mordechai, SE Sharon… - Journal of the Mechanical …, 2023 - Elsevier
Soft tissues are constructed as fiber-reinforced composites consisting of structural
mechanisms and unique mechanical behavior. Biomimetics of their mechanical behavior is …

Lipoplex‐Functionalized Thin‐Film Surface Coating Based on Extracellular Matrix Components as Local Gene Delivery System to Control Osteogenic Stem Cell …

C Husteden, YA Brito Barrera… - Advanced …, 2023 - Wiley Online Library
A gene‐activated surface coating is presented as a strategy to design smart biomaterials for
bone tissue engineering. The thin‐film coating is based on polyelectrolyte multilayers …

Structure-function characterization of the transition zone in the intervertebral disc

M Mirzaeipoueinak, HS Mordechai, SS Bangar… - Acta Biomaterialia, 2023 - Elsevier
Understanding the structure-function relationship in the intervertebral disk (IVD) is crucial for
the development of novel tissue engineering strategies to regenerate IVD and the …

Collagen-based micro/nano fibrous constructs: Step-by-step reverse biomimetics of structure and mechanical function

SE Sharon, A Aharonov, HS Mordechai… - ACS Applied Polymer …, 2023 - ACS Publications
Multiscale micro–nano fibrous structures are a cutting-edge research area in material
science and have drawn the attention of scientists in recent years. These structures are …

From Nature to Technology: Exploring Bioinspired Polymer Actuators via Electrospinning

MY Razzaq, M Balk, M Mazurek-Budzyńska… - Polymers, 2023 - mdpi.com
Nature has always been a source of inspiration for the development of novel materials and
devices. In particular, polymer actuators that mimic the movements and functions of natural …

Harnessing multifunctional collagen mimetic peptides to create bioinspired stimuli responsive hydrogels for controlled cell culture

EM Ford, AM Hilderbrand, AM Kloxin - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
The demand for synthetic soft materials with bioinspired structures continues to grow.
Material applications range from in vitro and in vivo tissue mimics to therapeutic delivery …

Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD …

JL Rosenberg, E Schaible, A Bostrom, AA Lazar… - PNAS …, 2023 - academic.oup.com
Understanding the biomechanical behavior of the intervertebral disc is crucial for studying
disease mechanisms and developing tissue engineering strategies for managing disc …