Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

Contact angle measurement is an effective way to investigate solid surface properties. The
introduction of low-cost digital cameras, as well as software and libraries for image analysis …

Abstract miRNA detection using microfluidics-based devices is one of the most important
innovations in biology and modern medicine. miRNAs are small regulatory molecules …

A major trend in biomedical engineering is the development of reliable, self-contained point-
of-care (POC) devices for diagnostics and in-field assays. The new generation of such …

Liquid biopsy is now considered a valuable diagnostic tool for advanced metastatic non-
small cell lung cancer (NSCLC). In NSCLC, circulating tumor DNA (ctDNA) analysis has …

The biocompatibility of an implant depends upon the material it is composed of, in addition
to the prosthetic device's morphology, mechanical and surface properties. Properties as …

Exosomes are small extracellular vesicles well-studied both as cell signaling elements and
as source of highly informative biomarkers, in particular microRNAs. Standard techniques for …

Polydimethylsiloxane (PDMS) is a well-known biocompatible polymer employed for many
applications in the biomedical field. In this study, the biocompatibility and versatility of PDMS …

Abstract Two Photon Polymerization (2PP) is a powerful additive manufacturing technology
already employed in the field of micro-/nano-engineering. The resolution achieved by 2PP …

Here we report a reduced graphene oxide-assisted rolling circle amplification for the
detection of miRNA SNPs. The difference of the signal of a miRNA SNP reaches 100 fold, a …