Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches

M Gioia, C Ciaccio, P Calligari, G De Simone… - Biochemical …, 2020 - Elsevier
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …

[HTML][HTML] Recent progress in the drug development targeting SARS-CoV-2 main protease as treatment for COVID-19

W Cui, K Yang, H Yang - Frontiers in molecular biosciences, 2020 - frontiersin.org
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2)
rapidly turned into an unprecedented pandemic of coronavirus disease 2019 (COVID-19) …

Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies

SA Cherrak, H Merzouk, N Mokhtari-Soulimane - Plos one, 2020 - journals.plos.org
A novel coronavirus responsible of acute respiratory infection closely related to SARS-CoV
has recently emerged. So far there is no consensus for drug treatment to stop the spread of …

Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity …

MTJ Quimque, KIR Notarte… - Journal of …, 2021 - Taylor & Francis
The novel coronavirus SARS-CoV2, the causative agent of the pandemic disease COVID-
19, emerged in December 2019 forcing lockdown of communities in many countries. The …

In-Silico approach for identification of effective and stable inhibitors for COVID-19 main protease (Mpro) from flavonoid based phytochemical constituents of Calendula …

P Das, R Majumder, M Mandal… - Journal of Biomolecular …, 2021 - Taylor & Francis
The recent outbreak of the coronavirus disease COVID-19 is putting the world towards a
great threat. A recent study revealed COVID-19 main protease (Mpro) is responsible for the …

[HTML][HTML] An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

S Bastani, V Vahedian, M Rashidi, A Mir… - Biomedicine & …, 2022 - Elsevier
Crocin, an active ingredient derived from saffron, is one of the herbal components that has
recently been considered by researchers. Crocin has been shown to have many anti …

A review on potential of natural products in the management of COVID-19

R Chakravarti, R Singh, A Ghosh, D Dey, P Sharma… - RSC …, 2021 - pubs.rsc.org
At the end of 2019, a life threatening viral infection (COVID-19) caused by a novel
coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was …

Comprehensive virtual screening of the antiviral potentialities of marine polycyclic guanidine alkaloids against SARS-CoV-2 (COVID-19)

A El-Demerdash, AM Metwaly, A Hassan… - Biomolecules, 2021 - mdpi.com
The huge global expansion of the COVID-19 pandemic caused by the novel SARS-corona
virus-2 is an extraordinary public health emergency. The unavailability of specific treatment …

Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules …

SA Amin, K Ghosh, S Gayen, T Jha - Journal of Biomolecular …, 2021 - Taylor & Francis
Abstract World Health Organization characterized novel coronavirus disease (COVID-19),
caused by severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) as …

Phylogenetic analysis and structural perspectives of RNA-dependent RNA-polymerase inhibition from SARs-CoV-2 with natural products

A Khan, M Khan, S Saleem, Z Babar, A Ali… - Interdisciplinary …, 2020 - Springer
Most recently, an outbreak of severe pneumonia caused by the infection of SARS-CoV-2, a
novel coronavirus first identified in Wuhan, China, imposes serious threats to public health …