[HTML][HTML] COVID-19 and severity of liver diseases: Possible crosstalk and clinical implications

MT Imam, ZS Almalki, AR Alzahrani… - International …, 2023 - Elsevier
COVID-19-infected individuals and those who recovered from the infection have been
demonstrated to have elevated liver enzymes or abnormal liver biochemistries, particularly …

The effect of nitazoxanide on the clinical outcomes in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials

M Abuelazm, A Ghanem, AK Awad, RA Farahat… - Clinical Drug …, 2022 - Springer
Abstract Background and Objective Nitazoxanide, a US Food and Drug Administration-
approved antiparasitic agent, was reported to be effective in treating coronavirus disease …

[HTML][HTML] Novel scaffolds identification against Mpro of SARS-CoV-2 using shape based screening and molecular simulation methods

P Gupta, U Panwar, S Singh - Chemical Physics Impact, 2024 - Elsevier
Background Pfizer in the USA has pioneered an orally active drug called Nirmatrelvir (PF-
07321332) targeting the main protease (Mpro) protein of SARS-CoV-2. However, the current …

Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 …

S Gamal, GG Mohamed, SA Salih, MI Ezzeldin… - Future Journal of …, 2023 - Springer
Abstract Background Sofosbuvir/ledipasvir (SOF/LDV), a combination of antiviral drugs, has
been recently repurposed for COVID-19 management, according to Food and Drug …

Simultaneous spectrophotometric determination of recombined sofosbuvir, ledipasvir and paracetamol together as commonly repurposed drugs for COVID-19 …

S Gamal, AA Mandour, GG Mohamed, SA Salih… - Future Journal of …, 2023 - Springer
Background COVID-19 has emerged as the most serious outbreak in recent years. Certain
medications such as sofosbuvir (SOF), ledipasvir (LDV) and paracetamol (PAR) were …

Computational insights into pediatric adenovirus inhibitors: in silico strategies for drug repurposing

K Sarkar, S Nandi, RK Das - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Human adenovirus (HADV) infection can pose a serious threat to children, leading to a
variety of respiratory illnesses and other complications. Particularly, children with weak …

Clinical outcomes, virological efficacy and safety of nitazoxanide in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized …

TC Weng, TS Weng, CC Lai, CM Chao… - Expert Review of Anti …, 2022 - Taylor & Francis
Background This study investigated the clinical outcomes, virological efficacy and safety of
nitazoxanide in the treatment of patients with COVID-19. Research design and methods The …

[HTML][HTML] Can Nitazoxanide and/or other anti‐viral medications be a solution to long COVID? Case report with a brief literature review

DD Stewart - Clinical Case Reports, 2023 - ncbi.nlm.nih.gov
Long COVID or post‐acute sequelae of COVID‐19 (PASC) continues to affect many people
even after a relatively mild acute illness. Underlying causes of PASC are poorly understood …

PHYSICOCHEMICAL AND PHARMACOKINETIC ANALYSIS AND DOCKING OF DRUG REPOSITIONING AGAINST SARS-COV-2: AN IN SILICO STUDY.

JA Pereira, ED Costa - Indian Drugs, 2024 - search.ebscohost.com
Studies on the development of effective and cost-effective oral drugs are the new priority of
the pharmaceutical industry for the prevention and treatment of COVID-19. This work was …