Tumor-associated macrophages and inflammatory microenvironment in gastric cancer: novel translational implications

K Rihawi, AD Ricci, A Rizzo, S Brocchi… - International Journal of …, 2021 - mdpi.com
Gastric cancer (GC) represents the fifth most frequently diagnosed cancer worldwide, with a
poor prognosis in patients with advanced disease despite many improvements in systemic …

Reactive oxygen species in the adverse outcome pathway framework: Toward creation of harmonized consensus key events

S Tanabe, J O'Brien, KE Tollefsen, Y Kim… - Frontiers in …, 2022 - frontiersin.org
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result
of natural cellular processes, intracellular signaling, or as adverse responses associated …

[HTML][HTML] Luteolin inhibits subretinal fibrosis and epithelial-mesenchymal transition in laser-induced mouse model via suppression of Smad2/3 and YAP signaling

C Zhang, Y Zhang, X Hu, Z Zhao, Z Chen, X Wang… - Phytomedicine, 2023 - Elsevier
Background Subretinal fibrosis (SF) accounts for vision loss in patients with neovascular age-
related macular degeneration (nAMD) even treated with adequate intravitreal injection of …

Helicobacter pylori Infection and Extragastric Diseases—A Focus on the Central Nervous System

J Baj, A Forma, W Flieger, I Morawska, A Michalski… - Cells, 2021 - mdpi.com
Helicobacter pylori (H. pylori) is most known to cause a wide spectrum of gastrointestinal
impairments; however, an increasing number of studies indicates that H. pylori infection …

Anticancer effects and mechanisms of astragaloside-IV

L Zhou, M Li, Z Chai, J Zhang, K Cao… - Oncology …, 2022 - spandidos-publications.com
Astragalus membranaceus Bunge is widely used in Traditional Chinese Medicine to treat
various cancers. Astragaloside-IV (AS-IV) is one of the major compounds isolated from A …

Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis

M Song, Z Li, H Gu, R Tang, R Zhang… - Journal of …, 2021 - Wiley Online Library
Background. Ganoderma lucidum has certain components with known pharmacological
effects, including strengthening immunity and anti‐inflammatory activity. G. lucidum seeds …

Anticancer plant-derivatives: Deciphering their oncopreventive and therapeutic potential in molecular terms

R Gahtori, AH Tripathi, A Kumari, N Negi… - Future Journal of …, 2023 - Springer
Background Over the years, phytomedicines have been widely used as natural modalities
for the treatment and prevention of various diseases by different ethnic groups across the …

Progress of tumor-associated macrophages in the epithelial-mesenchymal transition of tumor

X Li, L Chen, X Peng, X Zhan - Frontiers in Oncology, 2022 - frontiersin.org
As a significant public health problem with high morbidity and mortality worldwide, tumor is
one of the major diseases endangering human life. Moreover, metastasis is the most …

Overcoming therapeutic resistance to platinum-based drugs by targeting Epithelial–Mesenchymal transition

X Duan, M Luo, J Li, Z Shen, K Xie - Frontiers in oncology, 2022 - frontiersin.org
Platinum-based drugs (PBDs), including cisplatin, carboplatin, and oxaliplatin, have been
widely used in clinical practice as mainstay treatments for various types of cancer. Although …

Construction and validation of a novel coagulation-related 7-gene prognostic signature for gastric cancer

B Wang, D Zou, N Wang, H Wang, T Zhang… - Frontiers in …, 2022 - frontiersin.org
Background: Gastric cancer (GC) is the most common malignant tumor. Due to the lack of
practical molecular markers, the prognosis of patients with advanced gastric cancer is still …