Tumor necrosis factor (TNF)‐α is a highly conserved proinflammatory cytokine with important
functions in immunity, tissue repair, and cellular homeostasis. Due to the simplicity of the …

Cells respond to invading pathogens and danger signals from the environment by adapting
gene expression to meet the need for protective effector molecules. While this innate …

JNK signaling is a critical regulator of inflammation and regeneration, but how it is controlled
in specific tissue contexts remains unclear. Here we show that, in the Drosophila intestine …

Tumor necrosis factor receptors (TNFRs) control pleiotropic pro-inflammatory functions that
range from apoptosis to cell survival. The ability to trigger a particular function will depend …

While the role of the Tumor necrosis factor-α (referred to as TNF here) as a key mediator of
pro-inflammatory and immune responses is well-established, non-pathological functions of …

Abstract Tumor Necrosis Factor-α (TNF-α) is a proinflammatory cytokine and a master
regulator of immune cell function in vertebrates. While previous studies have implicated TNF …

The activation of tumor necrosis factor receptors (TNFR) controls pleiotropic pro-
inflammatory functions ranging from apoptosis to survival. The ability to trigger a particular …

Cell communication via signalling exchange plays a pivotal role in multicellular
development for building functional tissues and organs. In the Drosophila testis, a pair of …