POC SCTs are not able to characterise the complexity of trauma-associated coagulopathy.
VETs provide a rapid estimation of underlying haemostatic disorders, thereby providing …

Viscoelastic tests provide a dynamic assessment of coagulation, by exploring the time to clot
formation and the clot strength. Using specific activators or inhibitors, additional factors can …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Platelets contract forcefully after their activation, contributing to the strength and stability of
platelet aggregates and fibrin clots during blood coagulation. Viscoelastic approaches can …

Platelets are damage sentinels of the intravascular compartment, initiating and coordinating
the primary response to tissue injury. Severe trauma and hemorrhage induce profound …

A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

Introduction: Trauma-induced coagulopathy (TIC) is a form of coagulopathy unique to
trauma patients and is associated with increased mortality. The complexity and incomplete …

Uncontrolled and massive bleeding with derangement of coagulation is a major challenge in
the management of both surgical and seriously injured patients. The underlying mechanism …

Trauma induces a change in nearly every observable aspect of hemostasis, generally
tipping the balance toward trauma-induced coagulopathy (TIC) and bleeding in the critical …

Objective Antiplatelet therapy has been a pillar of management for peripheral artery disease
(PAD). However, a significant subset of patients with PAD will be resistant to certain …