[HTML][HTML] Recent advances in improving oral drug bioavailability by cocrystals

S Emami, M Siahi-Shadbad, K Adibkia… - BioImpacts …, 2018 - ncbi.nlm.nih.gov
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Introduction: Oral drug delivery is the most favored route of drug administration. However …

Drug delivery of pH-Sensitive nanoparticles into the liver cancer cells

M Saadat, F Mostafaei, S Mahdinloo, M Abdi… - Journal of Drug Delivery …, 2021 - Elsevier
Nanotechnology is a developing strategy to overcome the disadvantages of traditional liver
cancer chemotherapy. For this purpose, different kinds of nanoparticles (NPs) regarding …

Layer-by-layer-coated lyotropic liquid crystalline nanoparticles for active tumor targeting of rapamycin

MS Freag, YSR Elnaggar, DA Abdelmonsif… - …, 2016 - Taylor & Francis
Aim: This work spotlights on fabrication of CD44-tropic, layer-by-layer (LbL) coated, liquid
crystalline nanoparticles of rapamycin (Rap-LbL-LCNPs) to enhance its water solubility and …

Influence of molecular structure and physicochemical properties of immunosuppressive drugs on micelle formulation characteristics and cutaneous delivery

J Quartier, M Lapteva, Y Boulaguiem, S Guerrier… - Pharmaceutics, 2023 - mdpi.com
The aim of this study was to investigate whether subtle differences in molecular properties
affected polymeric micelle characteristics and their ability to deliver poorly water-soluble …

Rapamycin loaded TPGS-Lecithins-Zein nanoparticles based on core-shell structure for oral drug administration

Z Xie, Z Zhang, H Lv - International journal of pharmaceutics, 2019 - Elsevier
Rapamycin as a novel macrolide immunosuppressive agent has been commonly used in
organ transplantation owing to its stronger immunosuppressive effect, non-nephrotoxicity …

Rapamycin-loaded immunoliposomes functionalized with trastuzumab: a strategy to enhance cytotoxicity to HER2-positive breast cancer cells

JO Eloy, R Petrilli, RW Brueggemeier… - Anti-Cancer Agents …, 2017 - ingentaconnect.com
Background: Liposomes have been employed to improve pharmacokinetics and reduce side
effects of drugs. They can be functionalized with antibodies for targeted delivery. While the …

Fabrication and characteristics of dual functionalized vascular stent by spatio-temporal coating

SM Kim, KS Park, E Lih, YJ Hong, JH Kang, IH Kim… - Acta Biomaterialia, 2016 - Elsevier
Stent implantation with balloon angioplasty is a widely used treatment for coronary artery
diseases. Stents have been developed from bare metal stent (BMS) to advanced forms such …

Characterization of excipients to improve pharmaceutical properties of sirolimus in the supercritical anti-solvent fluidized process

T Chen, Z Ma, Z Qiu, Z Zhong, L Xing, Q Guo… - International Journal of …, 2022 - Elsevier
Enhanced drug release and bioavailability of poorly soluble active pharmaceutical
ingredient (API) can be achieved via a fluidized bed coating integrated with supercritical anti …

Development of a Polymeric Pharmacological Nanocarrier System as a Potential Therapy for Spinocerebellar Ataxia Type 7

FV Borbolla-Jiménez, IA García-Aguirre… - Cells, 2023 - mdpi.com
Spinocerebellar ataxia type 7 (SCA7) is an autosomal-dominant inherited disease
characterized by progressive ataxia and retinal degeneration. SCA7 belongs to a group of …

Inhaled rapamycin solid lipid nano particles for the treatment of Lymphangioleiomyomatosis

E Landh, LM Moir, LG Dos Reis, D Traini… - European Journal of …, 2020 - Elsevier
Lymphangioleiomyomatosis (LAM) is a rare lung disease characterized by uncontrolled
growth of smooth muscle-like cells in the lungs that can spread via the lymphatic system to …