Obstructive sleep apnea syndrome (OSAS) is considered a low-grade chronic inflammatory
disease. Interleukin-6 (IL-6) is one of the most significant inflammatory markers and an …

Obstructive sleep apnoea (OSA) is associated with cardiovascular and metabolic
comorbidities, including hypertension, dyslipidaemia, insulin resistance and atherosclerosis …

Obstructive sleep apnoea (OSA) is a prevalent underdiagnosed disorder whose incidence
increases with age and weight. Uniquely characterised by frequent breathing interruptions …

Hypertriglyceridemia is a risk factor for a series of diseases, such as cardiovascular disease
(CVD), diabetes and nonalcoholic fatty liver disease (NAFLD). Angiopoietin-like proteins …

Obstructive sleep apnea (OSA) causes many systemic disorders via mechanisms related to
sympathetic nerve activation, systemic inflammation, and oxidative stress. OSA typically …

ANGPTL8 is an important cytokine, which is significantly increased in type 2 diabetes
mellitus (T2DM), obesity and metabolic syndrome. Many studies have shown that ANGPTL8 …

The occurrence and development of atherosclerosis could be influenced by intermittent
hypoxia. Obstructive sleep apnea (OSA), characterized by intermittent hypoxia, is world-wide …

Leucine-rich α-2 glycoprotein1 (LRG1) is a member of the leucine-rich repeat (LRR) family
that is implicated in multiple diseases, including cancer, aging, and heart failure, as well as …

Objective Obstructive sleep apnea (OSA) is a major risk factor for cardiovascular mortality.
Apnea-induced chronic intermittent hypoxia (CIH) is a primary pathophysiological …

Angiopoietin-like proteins (ANGPTL) is a family of eight members known to play an
important role in metabolic diseases. Of these, ANGPTL5 is suggested to regulate …