Age-related macular degeneration: A two-level model hypothesis

MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

Dendritic and synaptic protection: is it enough to save the retinal ganglion cell body and axon?

JB Morquette, A Di Polo - Journal of Neuro-Ophthalmology, 2008 - journals.lww.com
Glaucoma and other optic neuropathies have been traditionally viewed as diseases of the
optic nerve that lead to retinal ganglion cell (RGC) degeneration. Accordingly, the primary …

Acute retinal ganglion cell injury caused by intraocular pressure spikes is mediated by endogenous extracellular ATP

V Resta, E Novelli, G Vozzi, C Scarpa… - European Journal of …, 2007 - Wiley Online Library
Elevated intraocular pressure may lead to retinal ganglion cell injury and consequent visual
deficits. Chronic intraocular pressure increase is a major risk factor for glaucoma, a leading …

[HTML][HTML] Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography

KH Kim, M Puoris' haag, GN Maguluri… - Journal of …, 2008 - iovs.arvojournals.org
Progression of retinal degeneration in a mouse model was studied in vivo with high-
resolution spectral-domain optical coherence tomography (SD-OCT). Imaging in 3D with …

Two-photon targeted recording of GFP-expressing neurons for light responses and live-cell imaging in the mouse retina

W Wei, J Elstrott, MB Feller - Nature protocols, 2010 - nature.com
Cell type–specific green fluorescent protein (GFP) expression in the retina has been
achieved in an expanding repertoire of transgenic mouse lines, which are valuable tools for …

Optical coherence tomography study of experimental anterior ischemic optic neuropathy and histologic confirmation

JK Ho, MP Stanford, MA Shariati… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: The optic nerve is part of the central nervous system, and interruption of this
pathway due to ischemia typically results in optic atrophy and loss of retinal ganglion cells …

Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators

AC Weitz, MR Behrend, NS Lee… - Journal of …, 2013 - journals.physiology.org
Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus
bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from …

In vivo development of retinal ON-bipolar cell axonal terminals visualized in nyx:: MYFP transgenic zebrafish

EH Schroeter, ROL Wong, RG Gregg - Visual neuroscience, 2006 - cambridge.org
Axonal differentiation of retinal bipolar cells has largely been studied by comparing the
morphology of these interneurons in fixed tissue at different ages. To better understand how …

Expression analysis of green fluorescent protein in retinal neurons of four transgenic mouse lines

S Haverkamp, D Inta, H Monyer, H Wässle - Neuroscience, 2009 - Elsevier
Transgenic mice that express enhanced green fluorescent protein (EGFP) under the control
of a cell-specific promoter have been used with great success to identify and label specific …

In vivo confocal neuroimaging (ICON): non‐invasive, functional imaging of the mammalian CNS with cellular resolution

S Prilloff, J Fan, P Henrich‐Noack… - European journal of …, 2010 - Wiley Online Library
With in vivo confocal neuroimaging (ICON), single retinal ganglion cells (RGCs) can be
visualized non‐invasively, repeatedly, in real‐time and under natural conditions. Here we …