This review is based on our recent experience in producing the first commercial recombinant
proteins in transgenic plants. We bring forward the issues that have to be considered in the …

Over the past 15 years researchers have generated stable lines of several species of
transgenic fish important for aquaculture.'All-fish'growth hormone (GH) gene constructs and …

Recombinant human α 1-antitrypsin (rAAT) was expressed and secreted from transgenic
rice cell suspension cultures in its biologically active form. This was accomplished by …

Deficiency or abnormality of coagulation factor VIII (FVIII) causes a bleeding disorder called
hemophilia A. Treatment involves FVIII concentrates prepared from pooled human plasma or …

Haemophilia A is the most common inherited bleeding disorder caused by defects in the
F8C gene that encodes coagulation factor VIII. This X-linked recessive disorder occurs in …

The large scale production of recombinant collagen for use in biomaterials requires an
efficient expression system capable of processing a large (> 400 Kd) multisubunit protein …

This study was performed to develop a system for porcine somatic cell nuclear transfer
(SCNT) and to produce human erythropoietin (hEPO)-transgenic cloned piglets. Porcine …

Even very established companies have made mistakes when developing biosimilar
products. For example, not appreciating future threats to intellectual property caused a …

Molecular farming is an experimental application of biotechnology that involves the genetic
modification of crops for the production of proteins and chemicals for medicinal and …

Deficiency in a coagulation factor VIII (FVIII) causes a genetic disorder hemophilia A, which
is treated by repeated infusions of expensive FVIII products. Recombinant FVIII (rFVIII), the …