Intra-pancreatic fat deposition: bringing hidden fat to the fore
Abstract Development of advanced modalities for detection of fat within the pancreas has
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …
Metabolic implications of pancreatic fat accumulation
Fat accumulation outside subcutaneous adipose tissue often has unfavourable effects on
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …
Understanding the mechanisms of reversal of type 2 diabetes
Clinical and pathophysiological studies have shown type 2 diabetes to be a condition mainly
caused by excess, yet reversible, fat accumulation in the liver and pancreas. Within the liver …
caused by excess, yet reversible, fat accumulation in the liver and pancreas. Within the liver …
Hyperinsulinemia: an early indicator of metabolic dysfunction
DD Thomas, BE Corkey, NW Istfan… - Journal of the …, 2019 - academic.oup.com
Hyperinsulinemia is strongly associated with type 2 diabetes. Racial and ethnic minority
populations are disproportionately affected by diabetes and obesity-related complications …
populations are disproportionately affected by diabetes and obesity-related complications …
Deep learning to distinguish pancreatic cancer tissue from non-cancerous pancreatic tissue: a retrospective study with cross-racial external validation
Background The diagnostic performance of CT for pancreatic cancer is interpreter-
dependent, and approximately 40% of tumours smaller than 2 cm evade detection …
dependent, and approximately 40% of tumours smaller than 2 cm evade detection …
Type 2 diabetes: etiology and reversibility
R Taylor - Diabetes care, 2013 - Am Diabetes Assoc
metabolic control by either bariatric surgery or hypocaloric diet allows for the time sequence
of underlying pathophysiologic mechanisms to be observed. In reverse order, the same …
of underlying pathophysiologic mechanisms to be observed. In reverse order, the same …
Ectopic fat accumulation in the pancreas and its clinical relevance: a systematic review, meta-analysis, and meta-regression
Objective Growing evidence suggests that individuals with excessive fat in the pancreas are
at an increased risk of chronic metabolic disorders. The aim was to systematically review …
at an increased risk of chronic metabolic disorders. The aim was to systematically review …
Ethnicity and type 2 diabetes in the UK
LM Goff - Diabetic Medicine, 2019 - Wiley Online Library
Type 2 diabetes is a major UK public health priority. Among minority ethnic communities, the
prevalence is alarmingly high, approximately three to five times higher than in the white …
prevalence is alarmingly high, approximately three to five times higher than in the white …
2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial
Background The pancreas is small and irregular in shape in people with type 2 diabetes. If
these abnormalities are caused by the disease state itself rather than being a predisposing …
these abnormalities are caused by the disease state itself rather than being a predisposing …
[HTML][HTML] Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease
R Catanzaro, B Cuffari, A Italia… - World journal of …, 2016 - ncbi.nlm.nih.gov
After the first description of fatty pancreas in 1933, the effects of pancreatic steatosis have
been poorly investigated, compared with that of the liver. However, the interest of research is …
been poorly investigated, compared with that of the liver. However, the interest of research is …