Hydrogels for the repair of articular cartilage defects

KL Spiller, SA Maher, AM Lowman - Tissue engineering part B …, 2011 - liebertpub.com
The repair of articular cartilage defects remains a significant challenge in orthopedic
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …

Hydrogels for the application of articular cartilage tissue engineering: a review of hydrogels

EY Chuang, CW Chiang, PC Wong… - Advances in Materials …, 2018 - Wiley Online Library
The treatment of articular cartilage damage is a major task in the medical science of
orthopedics. Hydrogels possess the ability to form multifunctional cartilage grafts since they …

The enzymatic degradation and swelling properties of chitosan matrices with different degrees of N-acetylation

D Ren, H Yi, W Wang, X Ma - Carbohydrate Research, 2005 - Elsevier
In the design of chitosan-based drug delivery systems and implantable scaffolds, the
biodegradation rate of the chitosan matrix represents a promising strategy for drug delivery …

Swelling behavior of acrylic acid hydrogels prepared by γ-radiation crosslinking of polyacrylic acid in aqueous solution

E Jabbari, S Nozari - European Polymer Journal, 2000 - Elsevier
Swelling behavior of anionic acrylic acid polyelectrolyte hydrogel synthesized by γ-radiation
crosslinking of polyacrylic acid in aqueous solution was investigated. Cross-linked …

Nonlinear analysis of cartilage in unconfined ramp compression using a fibril reinforced poroelastic model

LP Li, J Soulhat, MD Buschmann, A Shirazi-Adl - Clinical Biomechanics, 1999 - Elsevier
Objective. To develop a biomechanical model for cartilage which is capable of capturing
experimentally observed nonlinear behaviours of cartilage and to investigate effects of …

Interstitial fluid pressurization during confined compression cyclical loading of articular cartilage

MA Soltz, GA Ateshian - Annals of biomedical engineering, 2000 - Springer
The objective of this study was to experimentally verify the well-accepted but untested
hypothesis that cartilage interstitial fluid pressurizes variously under the action of an applied …

Preparation of radiation cross-linked poly (Acrylic acid) hydrogel containing metronidazole with enhanced antibacterial activity

JO Jeong, JS Park, EJ Kim, SI Jeong, JY Lee… - International Journal of …, 2019 - mdpi.com
Metronidazole (MD) is known as a periodontitis medicine and has been widely used in
antibiotics for resistance to anaerobic bacteria, periodontal disease, and other threats. To …

Thermoreversible hydrogel scaffolds for articular cartilage engineering

JP Fisher, S Jo, AG Mikos… - Journal of Biomedical …, 2004 - Wiley Online Library
Articular cartilage has limited potential for repair. Current clinical treatments for articular
cartilage damage often result in fibrocartilage and are associated with joint pain and …

A study on the fabrication of porous chitosan/gelatin network scaffold for tissue engineering

F Shen, YL Cui, LF Yang, KD Yao, XH Dong… - Polymer …, 2000 - Wiley Online Library
A novel porous chitosan/gelatin scaffold for tissue engineering was prepared via
polyelectrolyte complex formation, freeze drying and post‐crosslinking with glutaraldehyde …

Thermally responsive microfibers mediated stem cell fate via reversibly dynamic mechanical stimulation

J Zhang, C Cheng, JL Cuellar‐Camacho… - Advanced Functional …, 2018 - Wiley Online Library
The role of mechanical forces is crucial for stem cell adhesion, viability, proliferation, self‐
renewal, and differentiation. The relationship between the natural extracellular matrix …